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Product Details
13651-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRAM1 Fusion Protein Ag4162 (1-299 aa encoded by BC028012)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAHHLPAAM ENHQDFRSIK AKFQASQPEP SDLPKKPPKP EFGKLKKFSQ PELSEHPKKA PLPEFGAVSL KPPPPEVTDL PKKPPPPEVT DLPKKPPPPE VTDLPKKPPP PEVTDLPKKP SKLELSDLSK KFPQLGATPF PRKPLQPEVG EAPLKASLPE PGAPARKPLQ PDELSHPARP PSEPKSGAFP RKLWQPEAGE ATPRSPQPEL STFPKKPAQP EFNVYPKKPP QPQVGGLPKK SVPQPEFSEA AQTPLWKPQS SEPKRDSSAF PKKASQPPLS DFPKKPPQPE LGDLTRTSSE (1-299 aa encoded by BC028012)
Target Information
The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC39864; PML-RARA target gene encoding an Adaptor Molecule-1; PML-RARA-regulated adapter molecule 1; PRAM; PRAM-1 protein
Gene Aliases: PML-RAR; PRAM-1; PRAM1
UniProt ID: (Human) Q96QH2
Entrez Gene ID: (Human) 84106
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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