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PRDM14 Antibody (MA5-27847) in ICC/IF
PRDM14 Monoclonal Antibody (GT1359) detects PRDM14 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: PRDM14 protein stained by PRDM14 Monoclonal Antibody (GT1359) (Product # MA5-27847) diluted at 1:1,000. Blue: Hoechst 33342 staining.
Product Details
MA5-27847
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
GT1359
Immunogen
Recombinant protein encompassing a sequence within the center region of human PRDM14. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735329
Product Specific Information
Predicted Reactivity: Mouse (82%), Bovine (91%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PRDM14 encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PR domain containing 14; PR domain zinc finger protein 14; PR domain-containing 14; PR domain-containing protein 14
Gene Aliases: PFM11; PRDM14
UniProt ID: (Human) Q9GZV8
Entrez Gene ID: (Human) 63978
negative regulation of transcription from RNA polymerase II promoter
cell morphogenesis
cell fate specification
inner cell mass cell fate commitment
transcription, DNA-templated
germ cell development
embryo implantation
fertilization
germ-line stem cell population maintenance
histone H3-R26 methylation
somatic stem cell population maintenance
negative regulation of fibroblast growth factor receptor signaling pathway
regulation of DNA methylation
homeostasis of number of cells within a tissue
inactivation of paternal X chromosome
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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