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Proteintech
PREP Polyclonal Antibody
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Product Details
11536-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PREP Fusion Protein Ag2101 (360-710 aa encoded by BC030636)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ILQLHDLTT GALLKTFPLD VGSIVGYSGQ KKDTEIFYQF TSFLSPGIIY HCDLTKEELE PRVFREVTVK GIDASDYQTV QIFYPSKDGT KIPMFIVHKK GIKLDGSHPA FLYGYGGFNI SITPNYSVSR LIFVRHMGGI LAVANIRGGG EYGETWHKGG ILANKQNCFD DFQCAAEYLI KEGYTSPKRL TINGGSNGGL LVAACANQRP DLFGCVIAQV GVMDMLKFHK YTIGHAWTTD YGCSDSKQHF EWLVKYSPLH NVKLPEADDI QYPSMLLLTA DHDDRVVPLH SLKFIATLQY IVGRSRKQSN PLLIHVDTKA GHGAGKPTAK VIEEVSDMFA FIARCLNVDW IP (360-710 aa encoded by BC030636)
Target Information
p33cdk2 associates with cyclin A in human cells. Kinase activity associated with cyclin A-cdc2 is found only in G2-phase. Cdk2 also complexes with cyclins E, D1, and D3. Cyclin E-cdk2 kinase is active in the G1- and S-phases of the cell cycle and is important (as does cyclin A-cdk2) for the progression from G1-to S-phase. The levels of cyclin A-cdk2 is maximal at the G1/S transition and both cdk2 and cyclin A are found associated with DNA in the initiation complex during replication. Rb protein acts as substrate for cdk2-cyclin E and/or cdk2-cyclin A in vivo. Cdk2 is activated and specifically localized to the nucleus during late G1-, S-, and G2-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: dJ355L5.1 (prolyl endopeptidase); EC 3.4.21.26; MGC16060; PE; PE {ECO:0000250|UniProtKB:P23687}; Post-proline cleaving enzyme; post-proline cleaving enzyme {ECO:0000250|UniProtKB:P23687}; prep {ECO:0000312|RGD:620841}; Prolyl endopeptidase; prolyl endopeptidase {ECO:0000250|UniProtKB:P23687}; prolyl oligopeptidase; rPop
Gene Aliases: AI047692; AI450383; D10Wsu136e; PE; PEP; Pop; PREP; rPop
UniProt ID: (Human) P48147, (Mouse) Q9QUR6, (Rat) O70196
Entrez Gene ID: (Human) 5550, (Mouse) 19072, (Rat) 83471
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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