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Immunogen sequence: QEMEGNLHQL SNPIGYRDLQ SHGRMHQSFD FDGGMAGSKL PGQEGVRIQP MSERTRRRAT SRDDNRRFRP HRSRRSRRSR SDNALHLASE REAISRLKDR PPLRAREDYD QFMRQRSFQE SMGHGSRRDL YGQCPRTVSD LALQNAFGDR WGPYFAEYDW CSTCSSSSES DNEGYFLGEP IPQPARLRYV TSDELLHKYS SYGLPKSSTL GGRGQLHSRK RQKSKNCIIS; Positive Samples: Mouse brain, Rat brain; Cellular Location: Nucleus membrane
This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5.
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Protein Aliases: DKFZp686D143; DKFZp686H1748; DKFZp686M031; EPM5p; PLP2; PRIC2; prickle homolog 2; prickle-like 2; Prickle-like protein 2
Gene Aliases: 6230400G14Rik; 6720451F06Rik; EPM5; mpk2; PRICKLE2
UniProt ID: (Human) Q7Z3G6, (Mouse) Q80Y24
Entrez Gene ID: (Human) 166336, (Rat) 312563, (Mouse) 243548
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