Proteintech

PROS1 Polyclonal Antibody

PROS1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

PROS1 Antibody (16910-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol) fixed HepG2 cells using 16910-1-AP (PROS1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PROS1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

16910-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:500

View 4 publications 4 publications

Flow Cytometry (Flow)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PROS1 Fusion Protein Ag10539 (328-676 aa encoded by BC015801)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.13 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: DFRTYDSEG VILYAESIDH SAWLLIALRG GKIEVQLKNE HTSKITTGGD VINNGLWNMV SVEELEHSIS IKIAKEAVMD INKPGPLFKP ENGLLETKVY FAGFPRKVES ELIKPINPRL DGCIRSWNLM KQGASGIKEI IQEKQNKHCL VTVEKGSYYP GSGIAQFHID YNNVSSAEGW HVNVTLNIRP STGTGVMLAL VSGNNTVPFA VSLVDSTSEK SQDILLSVEN TVIYRIQALS LCSDQQSHLE FRVNRNNLEL STPLKIETIS HEDLQRQLAV LDKAMKAKVA TYLGGLPDVP FSATPVNAFY NGCMEVNING VQLDLDEAIS KHNDIRAHSC PSVWKKTKNS (328-676 aa encoded by BC015801)

Target Information

Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Screening cell-cell communication in spatial transcriptomics via collective optimal transport.

Nature methods

Cang Z,Zhao Y,Almet AA,Stabell A,Ramos R,Plikus MV,Atwood SX,Nie Q

Wed Feb 01 00:00:00 UTC 2023

Multisample Mass Spectrometry-Based Approach for Discovering Injury Markers in Chronic Kidney Disease.

Molecular & cellular proteomics : MCP

Kim JE,Han D,Jeong JS,Moon JJ,Moon HK,Lee S,Kim YC,Yoo KD,Lee JW,Kim DK,Kwon YJ,Kim YS,Yang SH

Mon Mar 14 00:00:00 UTC 2022

CeRNA regulatory network-based analysis to study the roles of noncoding RNAs in the pathogenesis of intrahepatic cholangiocellular carcinoma.

Aging

Xu W,Yu S,Xiong J,Long J,Zheng Y,Sang X

Fri Jan 17 00:00:00 UTC 2020

CeRNA regulatory network-based analysis to study the roles of noncoding RNAs in the pathogenesis of intrahepatic cholangiocellular carcinoma.

Aging

Xu W,Yu S,Xiong J,Long J,Zheng Y,Sang X

Fri Jan 17 00:00:00 UTC 2020

The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.

Malaria journal

Tougan T,Edula JR,Morita M,Takashima E,Honma H,Tsuboi T,Horii T

Wed Apr 15 00:00:00 UTC 2020

The malaria parasite Plasmodium falciparum in red blood cells selectively takes up serum proteins that affect host pathogenicity.

Malaria journal

Tougan T,Edula JR,Morita M,Takashima E,Honma H,Tsuboi T,Horii T

Wed Apr 15 00:00:00 UTC 2020

Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions.

Frontiers in cellular neuroscience

Wisse LE,Penning R,Zaal EA,van Berkel CGM,Ter Braak TJ,Polder E,Kenney JW,Proud CG,Berkers CR,Altelaar MAF,Speijer D,van der Knaap MS,Abbink TEM

Wed Sep 30 00:00:00 UTC 2020

Proteomic and Metabolomic Analyses of Vanishing White Matter Mouse Astrocytes Reveal Deregulation of ER Functions.

Frontiers in cellular neuroscience

Wisse LE,Penning R,Zaal EA,van Berkel CGM,Ter Braak TJ,Polder E,Kenney JW,Proud CG,Berkers CR,Altelaar MAF,Speijer D,van der Knaap MS,Abbink TEM

Wed Sep 30 00:00:00 UTC 2020

The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity.

Science (New York, N.Y.)

Chan PY,Carrera Silva EA,De Kouchkovsky D,Joannas LD,Hao L,Hu D,Huntsman S,Eng C,Licona-Limón P,Weinstein JS,Herbert DR,Craft JE,Flavell RA,Repetto S,Correale J,Burchard EG,Torgerson DG,Ghosh S,Rothlin CV

Fri Apr 01 00:00:00 UTC 2016

The TAM family receptor tyrosine kinase TYRO3 is a negative regulator of type 2 immunity.

Science (New York, N.Y.)

Fri Apr 01 00:00:00 UTC 2016

Hereditary protein S deficiency leads to ischemic stroke.

Molecular medicine reports

Wang ZH,Zhao ZJ,Xu K,Sun GB,Song L,Yin HX,Chen XQ

Tue Sep 01 00:00:00 UTC 2015

Hereditary protein S deficiency leads to ischemic stroke.

Molecular medicine reports

Wang ZH,Zhao ZJ,Xu K,Sun GB,Song L,Yin HX,Chen XQ

Tue Sep 01 00:00:00 UTC 2015

Molecular basis of protein S deficiency in China.

American journal of hematology

Tang L,Jian XR,Hamasaki N,Guo T,Wang HF,Lu X,Wang QY,Hu Y

Tue Oct 01 00:00:00 UTC 2013

Molecular basis of protein S deficiency in China.

American journal of hematology

Tang L,Jian XR,Hamasaki N,Guo T,Wang HF,Lu X,Wang QY,Hu Y

Tue Oct 01 00:00:00 UTC 2013

Molecular basis of protein S deficiency in China.

American journal of hematology

Tang L,Jian XR,Hamasaki N,Guo T,Wang HF,Lu X,Wang QY,Hu Y

Tue Oct 01 00:00:00 UTC 2013

Molecular basis of protein S deficiency in China.

American journal of hematology

Tang L,Jian XR,Hamasaki N,Guo T,Wang HF,Lu X,Wang QY,Hu Y

Tue Oct 01 00:00:00 UTC 2013

Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-α overexpression.

American journal of physiology. Heart and circulatory physiology

Higuchi Y,Kubota T,Koyanagi M,Maeda T,Feldman AM,Makino N

Fri Jun 01 00:00:00 UTC 2012

Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-α overexpression.

American journal of physiology. Heart and circulatory physiology

Higuchi Y,Kubota T,Koyanagi M,Maeda T,Feldman AM,Makino N

Fri Jun 01 00:00:00 UTC 2012

Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-α overexpression.

American journal of physiology. Heart and circulatory physiology

Higuchi Y,Kubota T,Koyanagi M,Maeda T,Feldman AM,Makino N

Fri Jun 01 00:00:00 UTC 2012

Upregulation of anticoagulant proteins, protein S and tissue factor pathway inhibitor, in the mouse myocardium with cardio-specific TNF-α overexpression.

American journal of physiology. Heart and circulatory physiology

Higuchi Y,Kubota T,Koyanagi M,Maeda T,Feldman AM,Makino N

Fri Jun 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: Preproprotein S; PROS 1; Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS26; vitamin K-dependent plasma protein S; Vitamin K-dependent protein S

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Gene Aliases: AW214361; PROS; PROS1; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6

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UniProt ID: (Human) P07225, (Mouse) Q08761

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Entrez Gene ID: (Human) 5627, (Mouse) 19128

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Function(s)

endopeptidase inhibitor activity calcium ion binding protein complex binding

Process(es)

platelet degranulation signal peptide processing ER to Golgi vesicle-mediated transport blood coagulation negative regulation of endopeptidase activity peptidyl-glutamic acid carboxylation regulation of complement activation response to lipopolysaccharide fibrinolysis positive regulation of phagocytosis leukocyte migration hemostasis negative regulation of coagulation

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PROS1 Polyclonal Antibody

PROS1 Antibody (16910-1-AP) in ICC/IF

Product Details

16910-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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