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Invitrogen
PRP19 Recombinant Rabbit Monoclonal Antibody (SC06-53)
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FIGURE: 1 / 10
PRP19 Antibody (MA5-32222) in ICC/IF
Immunocytochemical analysis of PRP19 in B16-F1 cells using a PRP19 Monoclonal antibody (Product # MA5-32222) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32222
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SC06-53
Immunogen
recombinant protein within Human PRP19 aa 380-524
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809508
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
PSO4 is the human homolog of yeast Pso4, a gene essential for cell survival and DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hPso4; Neuronal differentiation-related gene protein; Nuclear matrix protein 200; nuclear matrix protein NMP200 related to splicing factor PRP19; nuclear matrix protein SNEV; Pre-mRNA-processing factor 19; prp19 beta; PRP19/PSO4 homolog; PRP19/PSO4 pre-mRNA processing factor 19 homolog; psoralen 4; RING-type E3 ubiquitin transferase PRP19; Senescence evasion factor
Gene Aliases: AA617263; AL024362; D19Wsu55e; hPSO4; NMP200; PRP19; PRPF19; PSO4; SNEV; UBOX4
UniProt ID: (Human) Q9UMS4, (Mouse) Q99KP6, (Rat) Q9JMJ4
Entrez Gene ID: (Human) 27339, (Mouse) 28000, (Rat) 246216
protein binding
ligase activity
ubiquitin-ubiquitin ligase activity
identical protein binding
ubiquitin protein ligase activity
ubiquitin-protein transferase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
protein polyubiquitination
spliceosomal tri-snRNP complex assembly
spliceosomal complex assembly
generation of catalytic spliceosome for first transesterification step
mRNA splicing, via spliceosome
inner cell mass cell proliferation
DNA repair
double-strand break repair via nonhomologous end joining
mRNA processing
cellular response to DNA damage stimulus
RNA splicing
lipid biosynthetic process
proteasomal protein catabolic process
protein ubiquitination
cellular protein localization
negative regulation of neuron differentiation
positive regulation of neuron differentiation
positive regulation of mRNA splicing, via spliceosome
positive regulation of astrocyte differentiation
protein K63-linked ubiquitination
signal transduction involved in DNA damage checkpoint
transcription-coupled nucleotide-excision repair
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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