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Proteintech
PRPF3 Polyclonal Antibody
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Product Details
10106-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRPF3 Fusion Protein Ag0154 (229-493 aa encoded by BC000184)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is a rabbit polyclonal antibody raised against an internal region of human PRPF3. A predicted molecular mass of 77 kDa and the gene is named PRPF3 because it is homologous to the yeast PRP3 gene. We noticed that although the predicted molecular mass of PRPF3 is77 kDa, the protein produced in E.coli migrated like a 90 kDa protein in SDS-PAGE.
Immunogen sequence: MVGLANLHA MGIAPPKVEL KDQTKPTPLI LDEQGRTVDA TGKEIELTHR MPTLKANIRA VKREQFKQQL KEKPSEDMES NTFFDPRVSI APSQRQRRTF KFHDKGKFEK IAQRLRTKAQ LEKLQAEISQ AARKTGIHTS TRLALIAPKK ELKEGDIPEI EWWDSYIIPN GFDLTEENPK REDYFGITNL VEHPAQLNPP VDNDTPVTLG VYLTKKEQKK LRRQTRREAQ KELQEKVRLG LMPPPEPKVR ISNLMRVLGT EAVQDP (229-493 aa encoded by BC000184)
Target Information
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs. The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: hPrp3; Pre-mRNA-splicing factor 3; PRP3 pre-mRNA processing factor 3 homolog; U4/U6 small nuclear ribonucleoprotein Prp3; U4/U6 snRNP 90 kDa protein; U4/U6-associated RNA splicing factor
Gene Aliases: 3632413F13Rik; HPRP3; HPRP3P; PRP3; Prp3p; PRPF3; RP18; SNRNP90
UniProt ID: (Human) O43395, (Mouse) Q922U1
Entrez Gene ID: (Human) 9129, (Rat) 361995, (Mouse) 70767
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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