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Immunogen sequence: MALSKRELDE LKPWIEKTVK RVLGFSEPTV VTAALNCVGK GMDKKKAADH LKPFLDDSTL RFVDKLFEAV EEGRSSRHSK SSSDRSRKRE LKEVFGDDSE ISKESSGVKK RRIPRFEEVE EEPEVIPGPP SESPGMLTKL QIKQMMEAAT RQIEERKKQL SFISPPTPQP KTPSSSQPER LPIGNTIQPS QAATFMNDAI EKARKAAELQ ARIQAQLALK PGLIGNANMV GLANLHAMGI APPKVELKDQ TKPTPLILDE QGRTVDATGK EIELTHRMPT; Positive Samples: MCF7, 22Rv1, A-549, HepG2, THP-1, BT-474, Mouse spleen, Mouse testis; Cellular Location: Nucleus speckle
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs. The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. PRPF3 is 1 of several proteins that associate with U4 and U6 snRNPs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hPrp3; Pre-mRNA-splicing factor 3; PRP3 pre-mRNA processing factor 3 homolog; U4/U6 small nuclear ribonucleoprotein Prp3; U4/U6 snRNP 90 kDa protein; U4/U6-associated RNA splicing factor
Gene Aliases: 3632413F13Rik; HPRP3; HPRP3P; PRP3; Prp3p; PRPF3; RP18; SNRNP90
UniProt ID: (Human) O43395, (Mouse) Q922U1
Entrez Gene ID: (Human) 9129, (Rat) 361995, (Mouse) 70767
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