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Sequence of this protein is as follows: MAQKGVLGPG QLGAVAILLY LGLLRSGTGA EGAEAPCGVA PQARITGGSS AVAGQWPWQV SITYEGVHVC GGSLVSEQWV LSAAHCFPSE HHKEAYEVKL GAHQLDSYSE DAKVSTLKDI IPHPSYLQEG SQGDIALLQL SRPITFSRYI RPICLPAANA SFPNGLHCTV TGWGHVAPSV SLLTPKPLQQ LEVPLISRET CNCLYNIDAK PEEPHFVQED MVCAGYVEGG KDACQGDSGG PLSCPVEGLW YLTGIVSWGD ACGARNRPGV YTLASSYASW IQSKVTELQP RVVPQTQESQ PDSNLCGSHL AFSSAPAQGL LRPILFLPLG LALGLLSPWL SEH
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAP1; channel activating protease 1; Channel-activating protease 1; Prostasin; protease, serine, 8 (prostasin); Serine protease 8
Gene Aliases: 2410039E18Rik; AI313909; C79772; CAP1; fr; mCAP1; PROSTASIN; PRSS8
UniProt ID: (Human) Q16651, (Rat) Q9ES87
Entrez Gene ID: (Human) 5652, (Mouse) 76560, (Rat) 192107
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