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Proteintech
PRUNE2 Polyclonal Antibody
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Product Details
11458-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PRUNE2 Fusion Protein Ag2025 (1-259 aa encoded by BC019095)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
The calculated molecular weight of this protein is 340 kDa. Our antibody specifically recognizes the 140-150 kDa band which is an isoform or cleaved fragment of PRUNE2.
Immunogen sequence: MEEFLQRAK SKLNRSKRLE KVHVVIGPKS CDLDSLISTF TYAYFLDKVS PPGVLCLPVL NIPRTEFNYF TETRFILEEL NISESFHIFR DEINLHQLND EGKLSITLVG SSVLASEDKT LESAVVKVIN PVEQSDANVE FRESSSSLVL KEILQEAPEL ITEQLAHRLR GSILFKWMTM ESEKISEKQE EILSILEEKF PNLPPREDII NVLQETQFSA QGLSIEQTML KDLKELSDGE IKVAISTVSM NLEVRVGMLF (1-259 aa encoded by BC019095)
Target Information
PRUNE2 gene, also named BMCC1, encodes protein prune homolog 2. PRUNE2 gene are overlapping with PCA3, one of the most prostate cancer specific markers. PRUNE2 may play an important role in regulating differentiation, survival and aggressiveness of the tumor cells. Besides its high level of expression seen in the nervous system (brain, cerebellum and spinal cord), it is also expressed at high levels in noneuroblastoma, rhabdomyosarcoma, melanoma and some osteosarcoma cell lines, whereas at only low levels in cancer cell lines of liver, breast, thyroid and colon. The Calculated molecular weight of this protein is 340 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A214N16.3; bA214N16.3; BCH motif-containing molecule at the carboxyl terminal region 1; BNIP2 motif containing molecule at the carboxyl terminal region 1; BNIP2 motif-containing molecule at the C-terminal region 1; DKFZp762K117; olfaxin; Protein prune homolog 2; RP11-214N16.3; RP11-58J3.2; truncated PRUNE2
Gene Aliases: BMCC1; BNIPXL; C9orf65; KIAA0367; PRUNE2
UniProt ID: (Human) Q8WUY3
Entrez Gene ID: (Human) 158471
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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