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Invitrogen
PRX Polyclonal Antibody
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FIGURE: 1 / 4
PRX Antibody (PA5-79887) in WB
Western blot analysis of PRX in Lane 1: rat kidney tissue lysate, Lane 2: mouse kidney tissue lysate, Lane 3: human 293T whole cell lysate, Lane 4: human HK-2 whole cell lysate using 50 µg (reducing conditions) per well. Electrophoresis was performed on 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours and protein was transferred to a nitrocellulose membrane at 150mA for 50-90 minutes. Sample was blocked with 5% Non-fat Milk/TBS for 1.5 hours at room temperature, incubated with PRX polyclonal antibody (Product # ... View More
Product Details
PA5-79887
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived human PRX recombinant protein (Position: M1-K91).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2747002
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Jurkat whole cell, human K562 whole cell, humna U2OS whole cell, human U251 whole cell, rat brain tissue, mouse brain tissue. Flow: K562 cell.
Target Information
Periaxin is a protein that in humans is encoded by the PRX gene. This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Periaxin
Gene Aliases: CMT4F; KIAA1620; L-Periaxin; PRX
UniProt ID: (Human) Q9BXM0, (Mouse) O55103, (Rat) Q63425
Entrez Gene ID: (Human) 57716, (Mouse) 19153, (Rat) 78960
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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