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Recommended positive controls: U87-MG, Rat brain.
Predicted reactivity: Mouse (98%), Rat (98%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PSD, which called EFA6A, is 63% identical to EFA6B (PSD4) and contains a Sec7 domain adjacent to a PH domain, followed by a C-terminal coiled-coil motif. This gene is mapped to chromosome 10q24. And it encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6; Exchange factor for ARF6; Exchange factor for ARF6 A; PH and SEC7 domain-containing protein 1; Pleckstrin homology and SEC7 domain-containing protein 1; pleckstrin-Sec7 domains-containing
Gene Aliases: EFA6; EFA6A; KIAA2011; PSD; PSD1; TYL
UniProt ID: (Human) A5PKW4
Entrez Gene ID: (Human) 5662, (Rat) 171381
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