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Invitrogen
PSIP1 Monoclonal Antibody (6E4)
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Product Details
MA5-15795
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
6E4
Immunogen
Purified recombinant fragment of human PSIP1 expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
ascites
Contains
0.03% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11153426
Product Specific Information
MA5-15795 targets PSIP1 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with Human, Non-human primate, and Rat samples.
The MA5-15795 immunogen is purified recombinant fragment of human PSIP1 expressed in E. Coli.
MA5-15795 detects PSIP1 which has a predicted molecular weight of approximately 75kDa.
Target Information
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CLL-associated antigen KW-7; dense fine speckles 70; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; mLEDGF; PC4 and SFRS1 interacting protein 2; PC4 and SFRS1-interacting protein; supercoiled DNA binding protein 75; transcriptional coactivator p52/p75; Transcriptional coactivator p75/p52
Gene Aliases: AA408851; AU015605; DFS70; LEDGF; Ledgfa; Ledgfb; p52; p75; PAIP; PSIP1; PSIP2; SBP75
UniProt ID: (Human) O75475, (Mouse) Q99JF8, (Rat) Q812D1
Entrez Gene ID: (Human) 11168, (Mouse) 101739, (Rat) 313323
mRNA 5'-splice site recognition
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
response to oxidative stress
response to heat
positive regulation of transcription from RNA polymerase II promoter
nuclear transport
establishment of integrated proviral latency
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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