Proteintech

PSPC1 Polyclonal Antibody

PSPC1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 6

PSPC1 Antibody (16714-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed PC-3 cells using 16714-1-AP (PSPC1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PSPC1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

16714-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:6,000

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PSPC1 Fusion Protein Ag10136 (1-351 aa encoded by BC014184)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.79 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MMLRGNLKQ VRIEKNPARL RALESAVGES EPAAAAAMAL ALAGEPAPPA PAPPEDHPDE EMGFTIDIKS FLKPGEKTYT QRCRLFVGNL PTDITEEDFK RLFERYGEPS EVFINRDRGF GFIRLESRTL AEIAKAELDG TILKSRPLRI RFATHGAALT VKNLSPVVSN ELLEQAFSQF GPVEKAVVVV DDRGRATGKG FVEFAAKPPA RKALERCGDG AFLLTTTPRP VIVEPMEQFD DEDGLPEKLM QKTQQYHKER EQPPRFAQPG TFEFEYASRW KALDEMEKQQ REQVDRNIRE AKEKLEAEME AARHEHQLML MRQDLMRRQE ELRRLEELRN QELQKRKQIQ LR (1-351 aa encoded by BC014184)

Target Information

Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line. Binds to poly(A), poly(G) and poly(U) RNA homopolymers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

K235 acetylation couples with PSPC1 to regulate the m⁶A demethylation activity of ALKBH5 and tumorigenesis.

Nature communications

Zhang XL,Chen XH,Xu B,Chen M,Zhu S,Meng N,Wang JZ,Zhu H,Chen D,Liu JB,Yan GR

Tue Jun 27 00:00:00 UTC 2023

The KDET Motif in the Intracellular Domain of the Cell Adhesion Molecule L1 Interacts with Several Nuclear, Cytoplasmic, and Mitochondrial Proteins Essential for Neuronal Functions.

International journal of molecular sciences

Kleene R,Loers G,Schachner M

Wed Jan 04 00:00:00 UTC 2023

The Interactions of the 70 kDa Fragment of Cell Adhesion Molecule L1 with Topoisomerase 1, Peroxisome Proliferator-Activated Receptor γ and NADH Dehydrogenase (Ubiquinone) Flavoprotein 2 Are Involved in Gene Expression and Neuronal L1-Dependent Functions.

International journal of molecular sciences

Loers G,Kleene R,Bork U,Schachner M

Fri Jan 20 00:00:00 UTC 2023

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Nucleic acids research

Fan J,Kuai B,Wang K,Wang L,Wang Y,Wu X,Chi B,Li G,Cheng H

Wed Sep 19 00:00:00 UTC 2018

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Nucleic acids research

Fan J,Kuai B,Wang K,Wang L,Wang Y,Wu X,Chi B,Li G,Cheng H

Wed Sep 19 00:00:00 UTC 2018

Bioinformatics

Protein Aliases: mPSP1; Paraspeckle component 1; Paraspeckle protein 1

View more View less

Gene Aliases: 5730470C09Rik; AI327109; AI449052; PSP1; PSPC1

View more View less

UniProt ID: (Human) Q8WXF1, (Rat) Q4KLH4, (Mouse) Q8R326

View more View less

Entrez Gene ID: (Human) 55269, (Rat) 305910, (Mouse) 66645

View more View less

Function(s)

nucleotide binding transcription regulatory region sequence-specific DNA binding core promoter binding protein binding poly(A) RNA binding RNA binding nucleic acid binding

Process(es)

transcription, DNA-templated regulation of circadian rhythm negative regulation of transcription, DNA-templated rhythmic process regulation of transcription, DNA-templated mRNA splicing, via spliceosome

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

PSPC1 Polyclonal Antibody

PSPC1 Antibody (16714-1-AP) in ICC/IF

Product Details

16714-1-AP

Western Blot (WB)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!