Product References
Phosphoglycerate dehydrogenase activates PKM2 to phosphorylate histone H3T11 and attenuate cellular senescence.
Nature communications
Wu Y,Tang L,Huang H,Yu Q,Hu B,Wang G,Ge F,Yin T,Li S,Yu X
Fri Mar 10 00:00:00 UTC 2023
Arginine limitation drives a directed codon-dependent DNA sequence evolution response in colorectal cancer cells.
Science advances
Hsu DJ,Gao J,Yamaguchi N,Pinzaru A,Wu Q,Mandayam N,Liberti M,Heissel S,Alwaseem H,Tavazoie S,Tavazoie SF
Fri Jan 06 00:00:00 UTC 2023
PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma.
Nature communications
Wang K,Luo L,Fu S,Wang M,Wang Z,Dong L,Wu X,Dai L,Peng Y,Shen G,Chen HN,Nice EC,Wei X,Huang C
Thu Feb 23 00:00:00 UTC 2023
PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma.
Nature communications
Wang K,Luo L,Fu S,Wang M,Wang Z,Dong L,Wu X,Dai L,Peng Y,Shen G,Chen HN,Nice EC,Wei X,Huang C
Thu Feb 23 00:00:00 UTC 2023
Ailanthone Inhibits Proliferation, Migration and Invasion of Osteosarcoma Cells by Downregulating the Serine Biosynthetic Pathway.
Frontiers in oncology
Zhang Y,Gong R,Liu Y,Sun X,Liang J,Zhou Y,Wang Y,Yu W,Wang Y,Tang L,He A,Shen Z,Yao Y,Hu H,Liu X,Zhang J
Wed Feb 23 00:00:00 UTC 2022
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Cell death & disease
Ruan Y,Hu J,Che Y,Liu Y,Luo Z,Cheng J,Han Q,He H,Zhou Q
Wed Feb 16 00:00:00 UTC 2022
The long noncoding RNA glycoLINC assembles a lower glycolytic metabolon to promote glycolysis.
Molecular cell
Zhu Y,Jin L,Shi R,Li J,Wang Y,Zhang L,Liang CZ,Narayana VK,De Souza DP,Thorne RF,Zhang LR,Zhang XD,Wu M
Thu Feb 03 00:00:00 UTC 2022
Phosphoserine phosphatase as an indicator for survival through potentially influencing the infiltration levels of immune cells in neuroblastoma.
Frontiers in cell and developmental biology
Zeng L,Liu XY,Chen K,Qin LJ,Wang FH,Miao L,Li L,Wang HY
Tue Sep 13 00:00:00 UTC 2022
Phosphoserine phosphatase as an indicator for survival through potentially influencing the infiltration levels of immune cells in neuroblastoma.
Frontiers in cell and developmental biology
Zeng L,Liu XY,Chen K,Qin LJ,Wang FH,Miao L,Li L,Wang HY
Tue Sep 13 00:00:00 UTC 2022
Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.
Molecular metabolism
Byles V,Cormerais Y,Kalafut K,Barrera V,Hughes Hallett JE,Sui SH,Asara JM,Adams CM,Hoxhaj G,Ben-Sahra I,Manning BD
Mon Nov 01 00:00:00 UTC 2021
Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism.
Cancer research
Cai LY,Chen SJ,Xiao SH,Sun QJ,Ding CH,Zheng BN,Zhu XY,Liu SQ,Yang F,Yang YX,Zhou B,Luo C,Zhang X,Xie WF
Mon Feb 15 00:00:00 UTC 2021
Targeting p300/CBP Attenuates Hepatocellular Carcinoma Progression through Epigenetic Regulation of Metabolism.
Cancer research
Cai LY,Chen SJ,Xiao SH,Sun QJ,Ding CH,Zheng BN,Zhu XY,Liu SQ,Yang F,Yang YX,Zhou B,Luo C,Zhang X,Xie WF
Mon Feb 15 00:00:00 UTC 2021
Bone metastatic breast cancer cells display downregulation of PKC-ζ with enhanced glutamine metabolism.
Gene
Tandon M,Othman AH,Winogradzki M,Pratap J
Mon Apr 05 00:00:00 UTC 2021
Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells.
Proceedings of the National Academy of Sciences of the United States of America
Wang J,Filippakis H,Hougard T,Du H,Ye C,Liu HJ,Zhang L,Hindi K,Bagwe S,Nijmeh J,Asara JM,Shi W,El-Chemaly S,Henske EP,Lam HC
Tue Sep 28 00:00:00 UTC 2021
Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation.
Cell metabolism
Shen L,Hu P,Zhang Y,Ji Z,Shan X,Ni L,Ning N,Wang J,Tian H,Shui G,Yuan Y,Li G,Zheng H,Yang XP,Huang D,Feng X,Li MJ,Liu Z,Wang T,Yu Q
Tue May 04 00:00:00 UTC 2021
Extracellular serine and glycine are required for mouse and human skeletal muscle stem and progenitor cell function.
Molecular metabolism
Gheller BJ,Blum JE,Lim EW,Handzlik MK,Hannah Fong EH,Ko AC,Khanna S,Gheller ME,Bender EL,Alexander MS,Stover PJ,Field MS,Cosgrove BD,Metallo CM,Thalacker-Mercer AE
Fri Jan 01 00:00:00 UTC 2021
CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner.
Molecular cancer
Liu X,Liu Y,Liu Z,Lin C,Meng F,Xu L,Zhang X,Zhang C,Zhang P,Gong S,Wu N,Ren Z,Song J,Zhang Y
Wed Sep 08 00:00:00 UTC 2021
CircMYH9 drives colorectal cancer growth by regulating serine metabolism and redox homeostasis in a p53-dependent manner.
Molecular cancer
Liu X,Liu Y,Liu Z,Lin C,Meng F,Xu L,Zhang X,Zhang C,Zhang P,Gong S,Wu N,Ren Z,Song J,Zhang Y
Wed Sep 08 00:00:00 UTC 2021
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism.
EMBO reports
Xu R,Jones W,Wilcz-Villega E,Costa AS,Rajeeve V,Bentham RB,Bryson K,Nagano A,Yaman B,Olendo Barasa S,Wang Y,Chelala C,Cutillas P,Szabadkai G,Frezza C,Bianchi K
Thu Sep 03 00:00:00 UTC 2020
The SIRT2/cMYC Pathway Inhibits Peroxidation-Related Apoptosis In Cholangiocarcinoma Through Metabolic Reprogramming.
Neoplasia (New York, N.Y.)
Xu L,Wang L,Zhou L,Dorfman RG,Pan Y,Tang D,Wang Y,Yin Y,Jiang C,Zou X,Wu J,Zhang M
Wed May 01 00:00:00 UTC 2019
PSPH Mediates the Metastasis and Proliferation of Non-small Cell Lung Cancer through MAPK Signaling Pathways.
International journal of biological sciences
Liao L,Ge M,Zhan Q,Huang R,Ji X,Liang X,Zhou X
Mon Dec 16 00:00:00 UTC 2019
PSPH Mediates the Metastasis and Proliferation of Non-small Cell Lung Cancer through MAPK Signaling Pathways.
International journal of biological sciences
Liao L,Ge M,Zhan Q,Huang R,Ji X,Liang X,Zhou X
Mon Dec 16 00:00:00 UTC 2019
PSPH Mediates the Metastasis and Proliferation of Non-small Cell Lung Cancer through MAPK Signaling Pathways.
International journal of biological sciences
Liao L,Ge M,Zhan Q,Huang R,Ji X,Liang X,Zhou X
Mon Dec 16 00:00:00 UTC 2019
PSPH Mediates the Metastasis and Proliferation of Non-small Cell Lung Cancer through MAPK Signaling Pathways.
International journal of biological sciences
Liao L,Ge M,Zhan Q,Huang R,Ji X,Liang X,Zhou X
Mon Dec 16 00:00:00 UTC 2019
A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition.
FEBS letters
Subedi A,Muroi M,Futamura Y,Kawamura T,Aono H,Nishi M,Ryo A,Watanabe N,Osada H
Mon Apr 01 00:00:00 UTC 2019
Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation.
Cell metabolism
Wang LW,Shen H,Nobre L,Ersing I,Paulo JA,Trudeau S,Wang Z,Smith NA,Ma Y,Reinstadler B,Nomburg J,Sommermann T,Cahir-McFarland E,Gygi SP,Mootha VK,Weekes MP,Gewurz BE
Tue Sep 03 00:00:00 UTC 2019
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.
Nature communications
Jin N,Bi A,Lan X,Xu J,Wang X,Liu Y,Wang T,Tang S,Zeng H,Chen Z,Tan M,Ai J,Xie H,Zhang T,Liu D,Huang R,Song Y,Leung EL,Yao X,Ding J,Geng M,Lin SH,Huang M
Thu Jun 20 00:00:00 UTC 2019
Berberine Inhibits Growth of Liver Cancer Cells by Suppressing Glutamine Uptake.
OncoTargets and therapy
Zhang P,Wang Q,Lin Z,Yang P,Dou K,Zhang R
Tue Apr 12 00:00:00 UTC 2022
Interfering Expression of Chimeric Transcript SEPT7P2-PSPH Promotes Cell Proliferation in Patients with Nasopharyngeal Carcinoma.
Journal of oncology
Wang J,Xie GF,He Y,Deng L,Long YK,Yang XH,Ma JJ,Gong R,Cen WJ,Ye ZL,Zeng YX,Wang HY,Shao JY
Fri Apr 08 00:00:00 UTC 2022
Interfering Expression of Chimeric Transcript SEPT7P2-PSPH Promotes Cell Proliferation in Patients with Nasopharyngeal Carcinoma.
Journal of oncology
Wang J,Xie GF,He Y,Deng L,Long YK,Yang XH,Ma JJ,Gong R,Cen WJ,Ye ZL,Zeng YX,Wang HY,Shao JY
Fri Apr 08 00:00:00 UTC 2022
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications.
Life science alliance
Tian S,Feng J,Cao Y,Shen S,Cai Y,Yang D,Yan R,Wang L,Zhang H,Zhong X,Gao P
Tue Oct 01 00:00:00 UTC 2019
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Science (New York, N.Y.)
Ben-Sahra I,Hoxhaj G,Ricoult SJH,Asara JM,Manning BD
Fri Feb 12 00:00:00 UTC 2016
mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle.
Science (New York, N.Y.)
Ben-Sahra I,Hoxhaj G,Ricoult SJH,Asara JM,Manning BD
Fri Feb 12 00:00:00 UTC 2016
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 UTC 2015
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 UTC 2015
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 UTC 2015
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 UTC 2015
