Abnova

PTAFR Polyclonal Antibody, MaxPab™

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

H00005724-B01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PTAFR (ACE87813.1, 1 a.a. approximately 342 a.a) full-length human protein.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Product may be used with Western Blot (Tissue lysate).

The Isotype of this product is composed of an IgG Mixture.

Immunogen sequence: MEPHDSSHMD SEFRYTLFPI VYSIIFVLGV IANGYVLWVF ARLYPCKKFN EIKIFMVNLT MADMLFLITL PLWIVYYQNQ GNWILPKFLC NVAGCLFFIN TYCSVAFLGV ITYNRFQAVT RPIKTAQANT RKRGISLSLV IWVAIVGAAS YFLILDSTNT VPDSAGSGNV TRCFEHYEKG SVPVLIIHIF IVFSFFLVFL IILFCNLVII RTLLMQPVQQ QRNAEVKRRA LWMVCTVLAV FIICFVPHHV VQLPWTLAEL GFQDSKFHQA INDAHQVTLC LLSTNCVLDP VIYCFLTKKF RKHLTEKFYS MRSSRKCSRA TTDTVTEVVV PFNQIPGNSL KN

Target Information

PTAFR shows structural characteristics of the rhodopsin gene family and binds platelet-activating factor (PAF). PAF is a phospholipid (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) that has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: PAF receptor; PAF-R; Platelet-activating factor receptor

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Gene Aliases: PAFR; PTAFR

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UniProt ID: (Human) P25105, (Mouse) Q62035

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Entrez Gene ID: (Human) 5724, (Mouse) 19204

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Function(s)
lipopolysaccharide binding lipopolysaccharide receptor activity G-protein coupled receptor activity platelet activating factor receptor activity phospholipid binding G-protein coupled purinergic nucleotide receptor activity mitogen-activated protein kinase binding signal transducer activity
Process(es)
cytokine production regulation of transcription from RNA polymerase II promoter chemotaxis inflammatory response immune response G-protein coupled receptor signaling pathway parturition response to symbiotic bacterium positive regulation of phospholipase C activity lipopolysaccharide-mediated signaling pathway positive regulation of tumor necrosis factor production inositol trisphosphate biosynthetic process G-protein coupled purinergic nucleotide receptor signaling pathway positive regulation of neutrophil degranulation transcytosis positive regulation of interleukin-6 biosynthetic process positive regulation of translation negative regulation of blood pressure positive regulation of vasoconstriction positive regulation of vasodilation phosphatidylinositol-mediated signaling positive regulation of smooth muscle cell proliferation interferon-gamma-mediated signaling pathway positive regulation of inositol phosphate biosynthetic process cellular response to gravity cellular response to cAMP cellular response to fatty acid response to dexamethasone positive regulation of voltage-gated chloride channel activity positive regulation of leukocyte tethering or rolling positive regulation of sensory perception of pain positive regulation of transcytosis positive regulation of maternal process involved in parturition positive regulation of gastro-intestinal system smooth muscle contraction cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine pattern recognition receptor signaling pathway signal transduction response to lipopolysaccharide
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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