PTEN Monoclonal Antibody (1B8)

magnesium ion binding phosphatidylinositol-3-phosphatase activity phosphoprotein phosphatase activity protein serine/threonine phosphatase activity protein tyrosine phosphatase activity platelet-derived growth factor receptor binding protein binding protein tyrosine/serine/threonine phosphatase activity lipid binding anaphase-promoting complex binding phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity enzyme binding protein kinase binding PDZ domain binding identical protein binding inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity hydrolase activity phosphatase activity

regulation of cyclin-dependent protein serine/threonine kinase activity angiogenesis negative regulation of protein phosphorylation regulation of B cell apoptotic process protein dephosphorylation phosphatidylinositol biosynthetic process apoptotic process neuron-neuron synaptic transmission synapse assembly central nervous system development heart development aging response to nutrient learning or memory memory locomotory behavior cell proliferation positive regulation of cell proliferation negative regulation of cell proliferation response to glucose response to zinc ion regulation of neuron projection development negative regulation of phosphatidylinositol 3-kinase signaling cell migration dentate gyrus development central nervous system neuron axonogenesis negative regulation of cell migration adult behavior negative regulation of myelination regulation of protein stability negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle regulation of synaptic transmission, GABAergic central nervous system myelin maintenance response to estradiol regulation of cellular component size regulation of myeloid cell apoptotic process response to ATP multicellular organismal response to stress social behavior peptidyl-tyrosine dephosphorylation response to drug maternal behavior negative regulation of apoptotic process protein kinase B signaling endothelial cell migration inositol phosphate metabolic process response to ethanol locomotor rhythm negative regulation of cell size negative regulation of organ growth response to arsenic-containing substance inositol phosphate dephosphorylation phosphatidylinositol dephosphorylation platelet-derived growth factor receptor signaling pathway phosphatidylinositol-mediated signaling regulation of axon regeneration cardiac muscle tissue development forebrain morphogenesis brain morphogenesis negative regulation of epithelial cell proliferation negative regulation of phagocytosis negative regulation of axonogenesis protein stabilization T cell receptor signaling pathway positive regulation of sequence-specific DNA binding transcription factor activity negative regulation of focal adhesion assembly negative regulation of protein kinase B signaling rhythmic synaptic transmission canonical Wnt signaling pathway synapse maturation prepulse inhibition male mating behavior long-term synaptic potentiation long term synaptic depression prostate gland growth dendritic spine morphogenesis negative regulation of dendritic spine morphogenesis negative regulation of ERK1 and ERK2 cascade positive regulation of ERK1 and ERK2 cascade cellular response to hypoxia negative regulation of ribosome biogenesis negative regulation of cell aging negative regulation of excitatory postsynaptic potential presynaptic membrane assembly postsynaptic density assembly positive regulation of TRAIL-activated apoptotic signaling pathway positive regulation of ubiquitin protein ligase activity positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process negative regulation of G1/S transition of mitotic cell cycle positive regulation of excitatory postsynaptic potential negative regulation of synaptic vesicle clustering lipid metabolic process nervous system development dephosphorylation neuron projection development cellular response to decreased oxygen levels positive regulation of apoptotic process regulation of cell cycle positive regulation of apoptotic signaling pathway