Invitrogen

PTGER2/PTGER3 Monoclonal Antibody (3F12)

View all (2) PTGER2/PTGER3 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

MA1-12677

Applications
Tested Dilution
Publications

Western Blot (WB)

1-5 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Clone

3F12

Immunogen

Recombinant human EP2 and EP3 receptor protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.11 mg/mL

Purification

Protein A/G

Storage buffer

PBS

Contains

0.08% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2269160

Product Specific Information

A suggested positive control for this product is porcine brain lysate.

Target Information

This polyclonal antibody was raised in Rabbit against PTGER3 / EP3. This antibody has been conjugated with Unconjugated. This antibody is useful for testing in the following assays: IHC-P. The specificity of this antibody has been described as follows: Human PTGER3 / EP3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: EP2 receptor; PGE receptor EP2 subtype; PGE receptor EP3 subtype; PGE receptor, EP2 subtype; PGE receptor, EP3 subtype; PGE2 receptor EP2 subtype; PGE2 receptor EP3 subtype; PGE2-R; prostaglandin E receotor EP3 subtype 3 isoform; prostaglandin E receptor 2 (EP2 subtype); prostaglandin E receptor 2 (subtype EP2), 53kD; prostaglandin E receptor 2 (subtype EP2), 53kDa; prostaglandin E receptor 3 (subtype EP3); prostaglandin E receptor EP2 subtype; prostaglandin E receptor EP3 subtype; prostaglandin E receptor subtype EP2; Prostaglandin E2 receptor EP2 subtype; Prostaglandin E2 receptor EP3 subtype; prostaglandin E2 receptor type 2; prostaglandin receptor (PGE-2); Prostanoid EP2 receptor; Prostanoid EP3 receptor

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Gene Aliases: EP2; EP3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3-VI; EP3e; PGE2-R; Pgerep3; Ptger-ep2; PTGER2; PTGER3; Ptgerep2; Ptgerep3; Rep3; rEP3a; rEP3b

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UniProt ID: (Human) P43116, (Human) P43115, (Rat) Q62928, (Mouse) Q62053, (Rat) P34980

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Entrez Gene ID: (Human) 5732, (Human) 5733, (Rat) 81752, (Mouse) 19217, (Rat) 24929, (Mouse) 19218

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Function(s)
prostaglandin E receptor activity signal transducer activity G-protein coupled receptor activity prostaglandin receptor activity protein binding
Process(es)
fever generation G-protein coupled receptor signaling pathway adenylate cyclase-modulating G-protein coupled receptor signaling pathway phospholipase C-activating G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration bicarbonate transport positive regulation of fever generation response to lipopolysaccharide positive regulation of urine volume skeletal system development adenylate cyclase-activating G-protein coupled receptor signaling pathway regulation of cell proliferation cellular response to prostaglandin E stimulus signal transduction desensitization of G-protein coupled receptor protein signaling pathway negative regulation of cAMP biosynthetic process positive regulation of cAMP biosynthetic process positive regulation of neutrophil extravasation inflammatory response female pregnancy cell death positive regulation of gene expression negative regulation of norepinephrine secretion intestine smooth muscle contraction urinary bladder smooth muscle contraction response to estradiol response to progesterone response to drug positive regulation of vasoconstriction positive regulation of circadian sleep/wake cycle, non-REM sleep negative regulation of insulin secretion maternal process involved in parturition negative regulation of gastric acid secretion cellular response to lipopolysaccharide cellular response to interleukin-1 negative regulation of platelet aggregation negative regulation of potassium ion transmembrane transport response to salt negative regulation of calcium ion transmembrane transport negative regulation of gastrin-induced gastric acid secretion positive regulation of smooth muscle contraction involved in micturition cellular response to forskolin positive regulation of inhibitory G-protein coupled receptor phosphorylation negative regulation of circadian sleep/wake cycle, wakefulness positive regulation of myofibroblast contraction positive regulation of colon smooth muscle contraction positive regulation of gastric mucosal blood circulation prostaglandin receptor internalization negative regulation of forebrain neuron differentiation
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