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Invitrogen
PTGES Recombinant Rabbit Monoclonal Antibody (13H2L6)
FIGURE: 1 / 3
PTGES Antibody (702796) in WB
Western blot analysis was performed on whole cell extracts (30 µg lysate) of MDA-MB-231 (Lane 1), MCF-7 (Lane 2), A549 (Lane 3), A-431 (Lane 4) and WJ-MSC (Wharton's Jelly-Derived Mesenchymal Stem Cells) (Lane 5) and tissue extract of Mouse testis (Lane 6). The blot was probed with Anti-PTGES Recombinant Rabbit Monoclonal Antibody (Product # 702796, 1:1000 dilution) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 1:5000 dilution). A ~17 kDa band co... View More
Product Details
702796
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Monoclonal
Type
Antibody
Clone
13H2L6
Immunogen
Peptides corresponding to human PTGES [1) aa42-aa58 2) aa1-aa12]
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2734827
Product Specific Information
This antibody is predicted to react with Monkey, Pig, Bovine.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
PTGES is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glutathione peroxidase PTGES; glutathione S-transferase 1-like 1; Glutathione transferase PTGES; MGST1-L1; MGST1-like 1; Microsomal glutathione S-transferase 1-like 1; Microsomal prostaglandin E synthase 1; microsomal prostaglandin E synthase-1; MPGES-1; p53-induced apoptosis protein 12; p53-induced gene 12 protein; Prostaglandin E synthase; tumor protein p53 inducible protein 12
Gene Aliases: 2410099E23Rik; D2Ertd369e; MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; MPGES1; PGES; PIG12; PP102; PP1294; PTGES; TP53I12
UniProt ID: (Human) O14684, (Mouse) Q9JM51
Entrez Gene ID: (Human) 9536, (Mouse) 64292
prostaglandin biosynthetic process
acute inflammatory response
chronic inflammatory response
prostaglandin metabolic process
signal transduction
negative regulation of cell proliferation
response to organic cyclic compound
cyclooxygenase pathway
response to lipopolysaccharide
response to retinoic acid
response to cytokine
response to calcium ion
lipid metabolic process
fatty acid metabolic process
fatty acid biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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