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Product Details
PA1-9532
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Chicken
/ IgY
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide based on human thymosin protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2174391
Product Specific Information
PA1-9532 detects Thymosin in human, mouse, pig and rat samples.
PA1-9532 has been successfully used in ELISA procedures.
PA1-9532 immunogen is a synthetic peptide based on human thymosin protein.
Target Information
The thymus gland produces several hormones or hormone-like substances which are derived from a polypeptide precursor containing (in the rat) 113 amino acids and known as prothymosin-alpha. A peptide containing 28 amino acid residues, named thymosin-alpha-1, was originally isolated from calf thymosin fraction 5 and shown to restore various aspects of immune function in several in vitro and invivo test systems. Thymosin-alpha-1 was subsequently isolated from a similar fraction from human thymosin and reported to have the same amino acid sequence as bovine thymosin-alpha-1. In 2003, Jiang et al. identified a pathway that regulates mitochondria-initiated caspase activity. In this pathway, putative human HLA class II-associated protein (PHAP) promoted caspase-9 activation after apoptosome formation, whereas prothymosin-alpha-1 negatively regulated caspase-9 activation by inhibiting apoptosome formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha-prothymosin; gene sequence 28; Prothymosin alpha; prothymosin alpha protein; prothymosin-alpha; thymosin; TMSB4; TMSB4X
Gene Aliases: PTMA; Thym; TMSA
UniProt ID: (Human) P06454, (Mouse) P26350, (Rat) P06302
Entrez Gene ID: (Human) 5757, (Pig) 100294684, (Mouse) 19231, (Rat) 29222
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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