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Invitrogen
PTPMT1 Polyclonal Antibody
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Product Details
PA5-60557
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PTPMT1. Recombinant protein control fragment (Product #RP-97310).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646121
Product Specific Information
Immunogen sequence: IPTLDNLQKG VQFALKYQSL GQCVYVHCKA GRSRSATMVA AYLIQVHKWS PEEAVRAIAK IRSYIHIRPG QLDVLKEFHK QITARAT
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 83%.
Target Information
Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: NB4 apoptosis/differentiation related protein; Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1; Phosphoinositide lipid phosphatase; Protein-tyrosine phosphatase mitochondrial 1; PTEN-like phosphatase
Gene Aliases: DUSP23; MOSP; PLIP; PNAS-129; PTPMT1
UniProt ID: (Human) Q8WUK0
Entrez Gene ID: (Human) 114971
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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