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PTPN23 Antibody (H00025930-B01P) in WB
Western Blot analysis of PTPN23 expression in transfected 293T cell line (H00025930-T02) by PTPN23 MaxPab polyclonal antibody.
Lane 1: PTPN23 transfected lysate(63.47 KDa).
Lane 2: Non-transfected lysate.
Lane 1: PTPN23 transfected lysate(63.47 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00025930-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PTPN23 (AAH04881, 1 a.a. approximately 577 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MGPQAAPLTI RGPSSAGQST PSPHLVPSPA PSPGPGPVPP RPPAAEPPPC LRRGAAAADL LSSSPESQHG GTQSPGGGQP LLQPTKVDAA EGRRPQALRL IERDPYEHPE RLRQLQQELE AFRGQLGDVG ALDTVWRELQ DAQEHDARGR SIAIARCYSL KNRHQDVMPY DSNRVVLRSG KDDYINASCV EGLSPYCPPL VATQAPLPGT AADFWLMVHE QKVSVIVMLV SEAEMEKQKV ARYFPTERGQ PMVHGALSLA LSSVRSTETH VERVLSLQFR DQSLKRSLVH LHFPTWPELG LPDSPSNLLR FIQEVHAHYL HQRPLHTPII VHCSSGVGRT GAFALLYAAV QEVEAGNGIP ELPQLVRRMR QQRKHMLQEK LHLRFCYEAV VRHVEQVLQR HGVPPPCKPL ASASISQKNH LPQDSQDLVL GGDVPISSIQ ATIAKLSIRP PGGLESPVAS LPGPAEPPGL PPASLPESTP IPSSSPPPLS SPLPEAPQPK EEPPVPEAPS SGPPSSSLEL LASLTPEAFS LDSSLRGKQR MSKHNFLQAH NGQGLRATRP SDDPLSLLDP LWTLNKT
Target Information
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HD-PTP; His domain-containing protein tyrosine phosphatase; Protein tyrosine phosphatase TD14; PTP-TD14; Tyrosine-protein phosphatase non-receptor type 23
Gene Aliases: HD-PTP; HDPTP; KIAA1471; PTP-TD14; PTPN23
UniProt ID: (Human) Q9H3S7
Entrez Gene ID: (Human) 25930
negative regulation of epithelial cell migration
protein transport
peptidyl-tyrosine dephosphorylation
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
cilium morphogenesis
positive regulation of homophilic cell adhesion
positive regulation of adherens junction organization
positive regulation of early endosome to late endosome transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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