Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 1
PTPRF Antibody (PA5-110242) in WB
Western blot analysis of PTPRF in BeWo cells. Samples were incubated with PTPRF Polyclonal antibody (Product # PA5-110242) using a dilution of 1:2,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Product Details
PA5-110242
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1016-1250 of human PTPRF (NP_0028312)
Conjugate
Form
Liquid
Concentration
2.6 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855653
Product Specific Information
Immunogen sequence: KNFRVAAAMK TSVLLSWEVP DSYKSAVPFK ILYNGQSVEV DGHSMRKLIA DLQPNTEYSF VLMNRGSSAG GLQHLVSIRT APDLLPHKPL PASAYIEDGR FDLSMPHVQD PSLVRWFYIV VVPIDRVGGS MLTPRWSTPE ELELDELLEA IEQGGEEQRR RRRQAERLKP YVAAQLDVLP ETFTLGDKKN YRGFYNRPLS PDLSYQCFVL ASLKEPMDQK RYASSPYSDE IVVQV
Target Information
Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: FLJ43335; FLJ45062; FLJ45567; LAR; LAR protein; LCA homolog; LCA-homolog; leukocyte antigen-related (LAR) PTP receptor; leukocyte antigen-related tyrosine phosphatase; Leukocyte common antigen related; protein tyrosine phosphatase, receptor type, F polypeptide; PTPRF protein; receptor-linked protein-tyrosine phosphatase LAR; Receptor-type tyrosine-protein phosphatase F
Gene Aliases: AA591035; BNAH2; LAR; LARS; PTPRF; RPTP-LAR
UniProt ID: (Human) P10586, (Mouse) A2A8L5
Entrez Gene ID: (Human) 5792, (Mouse) 19268
protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
heparin binding
protein complex binding
chondroitin sulfate proteoglycan binding
phosphoprotein phosphatase activity
insulin receptor binding
hydrolase activity
phosphatase activity
receptor tyrosine kinase binding
phosphate ion binding
negative regulation of cytokine-mediated signaling pathway
protein dephosphorylation
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
signal transduction
nervous system development
negative regulation of cell proliferation
regulation of neuron projection development
dephosphorylation
cell migration
neuron projection regeneration
negative regulation of cell projection organization
peptidyl-tyrosine dephosphorylation
negative regulation of epidermal growth factor receptor signaling pathway
positive regulation of apoptotic process
positive regulation of neuron apoptotic process
negative regulation of insulin receptor signaling pathway
regulation of axon regeneration
positive regulation of dendrite morphogenesis
regulation of synapse structure or activity
negative regulation of neurotrophin TRK receptor signaling pathway
negative regulation of receptor binding
transmembrane receptor protein tyrosine phosphatase signaling pathway
chemical synaptic transmission
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support