Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
H00005800-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3F4
Immunogen
PTPRO (AAH35960, 1 a.a. approximately 597 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MGHLPTGIHG ARRLLPLLWL FVLFKNATAF HVTVQDDNNI VVSLEASDVI SPASVYVVKI TGESKNYFFE FEEFNSTLPP PVIFKASYHG LYYIITLVVV NGNVVTKPSR SITVLTKPLP VTSVSIYDYK PSPETGVLFE IHYPEKYNVF TRVNISYWEG KDFRTMLYKD FFKGKTVFNH WLPGMCYSNI TFQLVSEATF NKSTLVEYSG VSHEPKQHRT APYPPQNISV RIVNLNKNNW EEQSGNFPEE SFMRSQDTIG KEKLFHFTEE TPEIPSGNIS SGWPDFNSSD YETTSQPYWW DSASAAPESE DEFVSVLPME YENNSTLSET EKSTSGSFSF FPVQMILTWL PPKPPTAFDG FHIHIEREEN FTEYLMVDEE AHEFVAELKE PGKYKLSVTT FSSSGSCETR KSQSAKSLSF YISPSGEWIE ELTEKPQHVS VHVLSSTTAL MSWTSSQENY NSTIVSVVSL TCQKQKESQR LEKQYCTQVN SSKPIIENLV PGAQYQVVIY LRKGPLIGPP SDPVTFAIVP TGIKDLMLYP LGPTAVVLSW TRPYLGVFRK YVVEMFYFNP ATMTSEWTTY YEIAATVSLT ASVVIFP
Target Information
Glomerular epithelial protein 1 (GLEPP1), also designated protein tyrosine phosphatase U2 (PTPase U2) or receptor-type tyrosine-protein phosphatase O (PTPRO), belongs to the protein-tyrosine phosphatase family. GLEPP1 is a Type I membrane protein containing 8 fibronectin type-III domains and 1 tyrosine-protein phosphatase domain. GLEPP1 is expressed primarily in the glomeruli of the kidney, but is also detected in placenta, lung and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: FMI; Glomerular epithelial protein 1; hPTP-J; osteoclastic transmembrane protein-tyrosine phosphatase; PCP-2; PCP2; phosphotyrosine phosphatase U2; protein tyrosine phosphatase PTP-U2; Protein tyrosine phosphatase U2; protein tyrosine phosphatase, receptor type, O; PTP phi; PTP pi; PTP-J; PTP-RO; PTP-U2; PTPase U2; PTPRU; R-PTP-O; R-PTP-psi; R-PTP-U; Receptor-type tyrosine-protein phosphatase O
Gene Aliases: GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPRO; PTPROT; PTPU2; R-PTP-O
UniProt ID: (Human) Q16827
Entrez Gene ID: (Human) 5800
cell morphogenesis
monocyte chemotaxis
regulation of glomerular filtration
negative regulation of glomerular filtration
protein dephosphorylation
axon guidance
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
lamellipodium assembly
glomerulus development
peptidyl-tyrosine dephosphorylation
slit diaphragm assembly
glomerular visceral epithelial cell differentiation
negative regulation of canonical Wnt signaling pathway
negative regulation of retinal ganglion cell axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support