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Proteintech
PTTG1IP Polyclonal Antibody
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Product Details
12575-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PTTG1IP Fusion Protein Ag3250 (1-180 aa encoded by BC012858)
Conjugate
Form
Liquid
Concentration
0.15 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAPGVARGP TPYWRLRLGG AALLLLLIPV AAAQEPPGAA CSQNTNKTCE ECLKNVSCLW CNTNKACLDY PVTSVLPPAS LCKLSSARWG VCWVNFEALI ITMSVVGGTL LLGIAICCCC CCRRKRSRKP DRSEEKAMRE REERRIRQEE RRAEMKTRHD EIRKKYGLFK EENPYARFEN N (1-180 aa encoded by BC012858)
Target Information
This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activation of basic fibroblast growth factor. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: PBF; Pituitary tumor-transforming gene 1 protein-interacting protein; Pituitary tumor-transforming gene protein-binding factor; PTTG-binding factor
Gene Aliases: C21orf1; C21orf3; PBF; PTTG1IP
UniProt ID: (Human) P53801
Entrez Gene ID: (Human) 754
protein import into nucleus
positive regulation of protein ubiquitination
negative regulation of DNA damage response, signal transduction by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of cellular protein catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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