Proteintech

PVRL1 Polyclonal Antibody

PVRL1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 4

PVRL1 Antibody (24713-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed SH-SY5Y cells using 24713-1-AP (PVRL1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PVRL1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

24713-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 3 publications 3 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PVRL1 Fusion Protein Ag20074 (31-334 aa encoded by BC104948)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: QVVQVNDSM YGFIGTDVVL HCSFANPLPS VKITQVTWQK STNGSKQNVA IYNPSMGVSV LAPYRERVEF LRPSFTDGTI RLSRLELEDE GVYICEFATF PTGNRESQLN LTVMAKPTNW IEGTQAVLRA KKGQDDKVLV ATCTSANGKP PSVVSWETRL KGEAEYQEIR NPNGTVTVIS RYRLVPSREA HQQSLACIVN YHMDRFKESL TLNVQYEPEV TIEGFDGNWY LQRMDVKLTC KADANPPATE YHWTTLNGSL PKGVEAQNRT LFFKGPINYS LAGTYICEAT NPIGTRSGQV EVNIT (31-334 aa encoded by B C104948)

Target Information

This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.

Journal of virology

Li XQ,Zeng L,Liang DG,Qi YL,Yang GY,Zhong K,Chu BB,Wang J

Thu Jun 29 00:00:00 UTC 2023

TMEM41B Is an Interferon-Stimulated Gene That Promotes Pseudorabies Virus Replication.

Journal of virology

Li XQ,Zeng L,Liang DG,Qi YL,Yang GY,Zhong K,Chu BB,Wang J

Thu Jun 29 00:00:00 UTC 2023

High expression of nectin-1 indicates a poor prognosis and promotes metastasis in hepatocellular carcinoma.

Frontiers in oncology

Wang X,Xing Z,Chen H,Yang H,Wang Q,Xing T

Wed Apr 12 00:00:00 UTC 2023

High expression of nectin-1 indicates a poor prognosis and promotes metastasis in hepatocellular carcinoma.

Frontiers in oncology

Wang X,Xing Z,Chen H,Yang H,Wang Q,Xing T

Wed Apr 12 00:00:00 UTC 2023

Oncolytic activity of naturally attenuated herpes-simplex virus HF10 against an immunocompetent model of oral carcinoma.

Molecular therapy oncolytics

Takano G,Esaki S,Goshima F,Enomoto A,Hatano Y,Ozaki H,Watanabe T,Sato Y,Kawakita D,Murakami S,Murata T,Nishiyama Y,Iwasaki S,Kimura H

Fri Mar 26 00:00:00 UTC 2021

Porphyromonas gingivalis induces penetration of lipopolysaccharide and peptidoglycan through the gingival epithelium via degradation of junctional adhesion molecule 1.

PLoS pathogens

Takeuchi H,Sasaki N,Yamaga S,Kuboniwa M,Matsusaki M,Amano A

Fri Nov 01 00:00:00 UTC 2019

Bioinformatics

Protein Aliases: CD111; ectodermal dysplasia 4 (Margarita Island type); herpes simplex virus type 1 sensitivity; Herpes virus entry mediator C; Herpesvirus entry mediator C; Herpesvirus Ig-like receptor; HIgR; nectin 1; Nectin cell adhesion molecule 1; Nectin-1; nectin-1 alpha; nectin-1 delta; poliovirus receptor-like 1; poliovirus receptor-related 1 (herpesvirus entry mediator C); Poliovirus receptor-related protein 1

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Gene Aliases: AI835281; AW549174; CD111; CLPED1; ED4; HIgR; HV1S; HVEC; nectin-1; NECTIN1; OFC7; PRR; PRR1; PVRL1; PVRR; PVRR1; SK-12

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UniProt ID: (Human) Q15223, (Mouse) Q9JKF6

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Entrez Gene ID: (Human) 5818, (Mouse) 58235

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Function(s)

virus receptor activity receptor binding protein binding coreceptor activity carbohydrate binding protein homodimerization activity virion binding protein heterodimerization activity cell adhesion molecule binding receptor activity

Process(es)

lens morphogenesis in camera-type eye desmosome organization iron ion transport cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules axon guidance viral process single organismal cell-cell adhesion viral entry into host cell camera-type eye morphogenesis regulation of synapse assembly retina development in camera-type eye enamel mineralization immune response signal transduction cell recognition adherens junction organization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PVRL1 Polyclonal Antibody

PVRL1 Antibody (24713-1-AP) in ICC/IF

Product Details

24713-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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