Proteintech

PVRL4 Polyclonal Antibody

PVRL4 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

PVRL4 Antibody (21903-1-AP) in ICC/IF

Immunofluorescent analysis of NIH/3T3 cells using 21903-1-AP (PVRL4 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PVRL4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

21903-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:2,000

Immunocytochemistry (ICC/IF)

1:20-1:200

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Product Specifications

Species Reactivity

Human, Mouse

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PVRL4 Fusion Protein Ag14127 (32-349 aa encoded by BC010423)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.41 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: GELETSDVV TVVLGQDAKL PCFYRGDSGE QVGQVAWARV DAGEGAQELA LLHSKYGLHV SPAYEGRVEQ PPPPRNPLDG SVLLRNAVQA DEGEYECRVS TFPAGSFQAR LRLRVLVPPL PSLNPGPALE EGQGLTLAAS CTAEGSPAPS VTWDTEVKGT TSSRSFKHSR SAAVTSEFHL VPSRSMNGQP LTCVVSHPGL LQDQRITHIL HVSFLAEASV RGLEDQNLWH IGREGAMLKC LSEGQPPPSY NWTRLDGPLP SGVRVDGDTL GFPPLTTEHS GIYVCHVSNE FSSRDSQVTV DVLDPQEDSG KQVDLVSAS (32-349 aa encoded by BC010423)

Target Information

Poliovirus receptor-like proteins (PVRLs), such as PVRL4, are adhesion receptors of the immunoglobulin superfamily and function in cell-cell adhesion.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Chemotherapy with gemcitabine and cisplatin downregulates tumor expression level of nectin-4 in a syngeneic model of murine MBT2 urothelial cancer cell line and C3H mice.

International journal of urology : official journal of the Japanese Urological Association

Miyake M,Oda Y,Nishimura N,Shimizu T,Fujii T,Fujimoto K

Wed Mar 01 00:00:00 UTC 2023

Chemotherapy with gemcitabine and cisplatin downregulates tumor expression level of nectin-4 in a syngeneic model of murine MBT2 urothelial cancer cell line and C3H mice.

International journal of urology : official journal of the Japanese Urological Association

Miyake M,Oda Y,Nishimura N,Shimizu T,Fujii T,Fujimoto K

Wed Mar 01 00:00:00 UTC 2023

Upregulation of nectin-4 is associated with ITGB1 and vasculogenic mimicry and may serve as a predictor of poor prognosis in colorectal cancer.

Oncology letters

Zhang J,Liu K,Peng P,Li S,Ye Z,Su Y,Liu S,Qin M,Huang J

Thu Aug 01 00:00:00 UTC 2019

MiR-31 and miR-128 regulates poliovirus receptor-related 4 mediated measles virus infectivity in tumors.

Molecular oncology

Geekiyanage H,Galanis E

Tue Nov 01 00:00:00 UTC 2016

MiR-31 and miR-128 regulates poliovirus receptor-related 4 mediated measles virus infectivity in tumors.

Molecular oncology

Geekiyanage H,Galanis E

Tue Nov 01 00:00:00 UTC 2016

Bioinformatics

Protein Aliases: Ig superfamily receptor LNIR; nectin 4; Nectin cell adhesion molecule 4; Nectin-4; poliovirus receptor-related 4; Poliovirus receptor-related protein 4

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Gene Aliases: 1200017F15Rik; EDSS1; LNIR; nectin-4; NECTIN4; PRR4; PVRL4

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UniProt ID: (Human) Q96NY8, (Mouse) Q8R007

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Entrez Gene ID: (Human) 81607, (Mouse) 71740

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Function(s)

virus receptor activity receptor activity receptor binding protein binding protein homodimerization activity cell adhesion molecule binding molecular_function

Process(es)

cell adhesion single organismal cell-cell adhesion homophilic cell adhesion via plasma membrane adhesion molecules heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules cell recognition adherens junction organization viral entry into host cell

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PVRL4 Polyclonal Antibody

PVRL4 Antibody (21903-1-AP) in ICC/IF

Product Details

21903-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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