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Invitrogen
PXDN Polyclonal Antibody
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PXDN Antibody (PA5-144080) in IHC (P)
Immunohistochemistry (Paraffin) analysis of PXDN in paraffin-embedded section of human pancreas cancer tissue using PXDN Polyclonal Antibody (Product # PA5-144080). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 1 µg/mL dilution overnigh... View More
Product Details
PA5-144080
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Human PXDN between 900-1064
Conjugate
Form
Liquid
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_3075294
Product Specific Information
Positive Control - WB: human Hela whole cell, human U251 whole cell, rat heart tissue, mouse heart tissue. IHC: human pancrease cancer tissue, human renal cancer tissue.
Target Information
Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hsPxd01; Melanoma-associated antigen MG50; p53-responsive gene 2 protein; PE responsive protein c64; Peroxidasin 1; Peroxidasin homolog; Vascular peroxidase 1
Gene Aliases: 2310075M15Rik; C85409; COPOA; D2S448; D2S448E; E330004E07; KIAA0230; MG50; mKIAA0230; Perc64; PRG2; PXD01; PXDN; PXN; VPO; VPO1
UniProt ID: (Human) Q92626, (Mouse) Q3UQ28
Entrez Gene ID: (Human) 7837, (Mouse) 69675, (Rat) 554172
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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