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Proteintech
PXMP3 Polyclonal Antibody
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Product Details
22163-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PXMP3 Fusion Protein Ag17815 (213-305 aa encoded by BC000661)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VQKLKAKLS SWCIPLTGAP NSDNTLATSG KECALCGERP TMPHTIGCEH IFCYFCAKSS FLFDVYFTCP KCGTEVHSLQ PLKSGIEMSE VNPL (213-305 aa encoded by B C000661)
Target Information
This gene encodes an integral peroxisomal membrane protein required for peroxisome biogenesis. The protein is thought to be involved in peroxisomal matrix protein import. Mutations in this gene result in one form of Zellweger syndrome and infantile Refsum disease. Alternative splicing results in multiple transcript variants encoding the same protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 35 kDa peroxisomal membrane protein; PAF-1; peroxin 2; Peroxin-2; Peroxisomal membrane protein 3; peroxisomal membrane protein 3, 35 kDa; peroxisomal membrane protein 3, 35kDa; Peroxisome assembly factor 1; peroxisome assembly factor-1; Peroxisome biogenesis factor 2; RING finger protein 72; Zellweger syndrome homolog
Gene Aliases: D3Ertd138e; PAF-1; PAF1; PBD5A; PBD5B; PEX2; PMP3; PMP35; PXMP3; RNF72; ZWS3
UniProt ID: (Human) P28328, (Mouse) P55098
Entrez Gene ID: (Human) 5828, (Mouse) 19302
very long-chain fatty acid metabolic process
negative regulation of transcription from RNA polymerase II promoter
protein polyubiquitination
neuron migration
fatty acid beta-oxidation
bile acid biosynthetic process
peroxisome organization
nervous system development
protein import into peroxisome matrix
protein destabilization
cholesterol homeostasis
regulation of cholesterol biosynthetic process
negative regulation of fibroblast proliferation
negative regulation of epithelial cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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