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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PYCR1 Antibodies

          Proteintech

          PYCR1 Polyclonal Antibody

          2 References
          View all (24) PYCR1 antibodies

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          Datasheet
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          Cite PYCR1 Polyclonal Antibody

          • Antibody Testing Data (7)
          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          PYCR1 Antibody (20962-1-AP) in IHC (P)

          Immunohistochemistry of paraffin-embedded human colon cancer using 20962-1-AP (PYCR1 antibody) at dilution of 1:50 (under 40x lens). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYCR1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Antibody in Western Blot (WB)
          PYCR1 Antibody in Immunoprecipitation (IP)

          Product Details

          20962-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Peptide

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.31 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Target Information

          This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: P5C reductase 1; P5CR 1; proliferation-inducing protein 45; Pyrroline-5-carboxylate reductase 1, mitochondrial

          View more View less

          Gene Aliases: ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222; PRO3; PYCR; PYCR1

          View more View less

          UniProt ID: (Human) P32322, (Mouse) Q922W5

          View more View less

          Entrez Gene ID: (Human) 5831, (Mouse) 209027

          View more View less

          Function(s)
          pyrroline-5-carboxylate reductase activity protein binding identical protein binding oxidoreductase activity
          Process(es)
          proline biosynthetic process cellular amino acid biosynthetic process cellular response to oxidative stress regulation of mitochondrial membrane potential oxidation-reduction process negative regulation of hydrogen peroxide-induced cell death L-proline biosynthetic process
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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