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          • Primary Antibodies ›
          • PYGO2 Antibodies

          Invitrogen

          PYGO2 Monoclonal Antibody (539730)

          1 Reference
          View all (10) PYGO2 antibodies

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          Datasheet
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          Datasheet
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          Cite PYGO2 Monoclonal Antibody (539730)

          • Antibody Testing Data (4)
          PYGO2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          PYGO2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          PYGO2 Antibody (MA5-24240) in ICC/IF

          Immunocytochemistry analysis of PYGO2 in immersion fixed MCF‚7 human breast cancer cell line. Samples were incubated in PYGO2 monoclonal antibody (Product # MA5-24240) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red, upper panel) and counterstained with DAPI (blue, lower panel). Specific staining was localized to nuclei. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          PYGO2 Antibody in Immunocytochemistry (ICC/IF)
          PYGO2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PYGO2 Antibody in Western Blot (WB)
          PYGO2 Antibody in Western Blot (WB)

          Product Details

          MA5-24240

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.5-5 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          3-25 µg/mL
          -

          Immunocytochemistry (ICC/IF)

          8-25 µg/mL
          -

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human

          Published species

          Human

          Host/Isotype

          Mouse / IgG2b

          Class

          Monoclonal

          Type

          Antibody

          Clone

          539730

          Immunogen

          E. coli-derived recombinant human Pygopus-2 Met160-Glu336
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          0.5 mg/mL

          Purification

          Protein A/G

          Storage buffer

          PBS with 5% trehalose

          Contains

          No Preservative

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2605750

          Product Specific Information

          In direct ELISAs, no cross-reactivity with recombinant human Pygopus-1 or recombinant mouse Pygopus-1 is observed.

          Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

          Target Information

          Involved in signal transduction through the Wnt pathway. [UniProt]

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: mpygo2; pygopus 2; Pygopus homolog 2

          View more View less

          Gene Aliases: 1190004M21Rik; PP7910; PYGO2

          View more View less

          UniProt ID: (Human) Q9BRQ0

          View more View less

          Entrez Gene ID: (Human) 90780

          View more View less

          Function(s)
          chromatin binding protein binding zinc ion binding histone acetyltransferase regulator activity histone binding
          Process(es)
          in utero embryonic development kidney development lens development in camera-type eye spermatid nucleus differentiation brain development post-embryonic development mammary gland development regulation of mammary gland epithelial cell proliferation regulation of histone acetylation positive regulation of chromatin binding developmental growth regulation of histone H3-K4 methylation palate development canonical Wnt signaling pathway beta-catenin-TCF complex assembly
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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