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Invitrogen
Pab1p Monoclonal Antibody (1G1)
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Product Details
MA5-47390
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bacteria,
Yeast
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
1G1
Immunogen
Yeast polyA binding protein preparations
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
cell culture media
Contains
5mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2942372
Target Information
The Pab1p protein was discovered in Saccharomyces cerevisia since it is abundant and binds specifically to the polyA tails of mRNA molecules. The systematic name in the Saccharomyces genome database is YER165w. It has a role in polyA length control in combination with Nab2p and may also be involved in mRNA stability and transcription. Pab1p is found in both the cytoplasm and nuclei of yeast cells and has a deduced molecular weight of 64 kDa, but runs on typical SDS-PAGE gels at about 67kDa. The yeast Pab1p protein sequence includes four RNA recognition motifs followed by a single C-terminal polyA binding domain. The closest human homolog of the yeast protein is polyadenylate-binding protein cytoplasmic 1-like (PABPC1L) which has the same domain structure, although is not well conserved in amino acid sequence. There are seven human genes encoding polyA binding proteins, four of which produce proteins with the same domain structure as yeast Pab1p and human PABPC1L.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARS consensus-binding protein ACBP-67; Pab1p; PABP; Poly(A) binding protein; Polyadenylate tail-binding protein; Polyadenylate-binding protein, cytoplasmic and nuclear
Gene Aliases: PAB1; YER165W
UniProt ID: (Baker's yeast) P04147
Entrez Gene ID: (Baker's yeast) 856912
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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