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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Pan Pax Antibodies

          Proteintech

          Pan-PAX Polyclonal Antibody

          5 References

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          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite Pan-PAX Polyclonal Antibody

          • Antibody Testing Data (10)
          Pan-PAX Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Pan-PAX Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 10

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          Pan-PAX Antibody (21383-1-AP) in ICC/IF

          Immunofluorescent analysis of ( -20°C Ethanol ) fixed SKOV-3 cells using 21383-1-AP (Pan-PAX antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Pan-PAX Antibody in Immunocytochemistry (ICC/IF)
          Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-PAX Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Pan-PAX Antibody in Western Blot (WB)
          Pan-PAX Antibody in Western Blot (WB)
          Pan-PAX Antibody in Immunoprecipitation (IP)

          Product Details

          21383-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (IHC)

          -
          View 3 publications 3 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 2 publications 2 publications

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Pig

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Pan-PAX Fusion Protein Ag16018

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.35 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody is a Pan-PAX antibody.

          Target Information

          This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Aniridia type II protein; B-cell lineage specific activator; B-cell-specific transcription factor; BSAP; Dickie's small eye; homeodomain protein PAX3; HuP1; HuP2; HuP48; Oculorhombin; optic disc coloboma; paired box gene 1; paired box gene 2; paired box gene 3; paired box gene 4; paired box gene 5; paired box gene 6; paired box gene 7; paired box gene 8; paired box gene 9; Paired box homeotic gene 1; paired box homeotic gene 2; paired box homeotic gene 3; paired box homeotic gene 5; paired box homeotic gene 6; paired box homeotic gene 7; paired box homeotic gene-6; Paired box protein Pax-1; Paired box protein Pax-2; Paired box protein Pax-3; Paired box protein Pax-4; Paired box protein Pax-5; Paired box protein Pax-6; Paired box protein Pax-7; Paired box protein Pax-8; Paired box protein Pax-9; paired box transcription factor PAX7; paired domain gene 3; paired domain gene 4; paired domain gene 5; paired domain gene 7; paired domain gene 8; paired domain gene 9; paired domain gene HuP2; paired domain gene HuP48; Pax-8 protein; PAX3/FKHR fusion; Pax5 variant 1; Pax5 variant 2; PAX7 transcriptional factor; pax9 {ECO:0000312|EMBL:BAE79272.1}; small eye; transcription factor PAX 5; wavy tail

          View more View less

          Gene Aliases: 1500038E17Rik; AEY11; ALL3; AN; AN2; BSAP; CDHS; D11S812E; Dey; EBB-1; FSGS7; FVH1; Gsfaey11; hbs; hunchback; HUP1; HUP2; HUP48; KLP; KPD; MGDA; MODY9; OFC2; Opdc; PAPRS; Pax-1; Pax-2; Pax-3; Pax-4; Pax-5; Pax-6; Pax-7; Pax-8; Pax-9; PAX1; PAX2; PAX3; Pax4; PAX5; PAX6; PAX7; PAX7B; PAX8; PAX9; RGD1564360; RGD1565236; RMS2; Sey; Sp; splotch; STHAG3; un; undulated; WAGR; WS1; WS3; wt

          View more View less

          UniProt ID: (Human) P15863, (Human) Q02962, (Human) P23760, (Human) Q02548, (Human) P26367, (Human) P23759, (Human) Q06710, (Human) P55771, (Mouse) P09084, (Mouse) P32114, (Mouse) P24610, (Rat) O88436, (Mouse) P32115, (Mouse) Q02650, (Mouse) P63015, (Rat) P63016, (Mouse) P47239, (Mouse) Q00288, (Rat) P51974, (Rat) Q2L4T2, (Mouse) P47242

          View more View less

          Entrez Gene ID: (Human) 5075, (Human) 5076, (Human) 5077, (Human) 5078, (Human) 5079, (Human) 5080, (Human) 5081, (Human) 7849, (Human) 5083, (Rat) 311505, (Mouse) 18503, (Rat) 293992, (Mouse) 18504, (Rat) 114502, (Mouse) 18505, (Rat) 83630, (Mouse) 18506, (Rat) 500453, (Mouse) 18507, (Mouse) 18508, (Rat) 25509, (Rat) 500574, (Mouse) 18509, (Mouse) 18510, (Rat) 81819, (Rat) 362741, (Mouse) 18511

          View more View less

          Function(s)
          DNA binding transcription factor activity, sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding protein binding transcription factor binding superoxide-generating NADPH oxidase activity transcription regulatory region DNA binding sequence-specific DNA binding HMG box domain binding RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II core promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding ubiquitin-protein transferase activity protein kinase binding ubiquitin protein ligase binding histone acetyltransferase binding co-SMAD binding R-SMAD binding transcription factor activity, RNA polymerase II core promoter sequence-specific thyroid-stimulating hormone receptor activity RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding C2H2 zinc finger domain binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding double-stranded DNA binding AT DNA binding molecular_function
          Process(es)
          transcription from RNA polymerase II promoter endoderm development odontogenesis regulation of odontogenesis negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter face morphogenesis cellular response to growth factor stimulus apoptotic process nervous system development muscle organ development sensory perception of sound organ morphogenesis neural crest formation positive regulation of transcription, DNA-templated skeletal system development somitogenesis cell proliferation CD4-positive, alpha-beta T cell differentiation CD8-positive, alpha-beta T cell differentiation thymus development parathyroid gland development bone morphogenesis sclerotome development chromatin remodeling regulation of transcription from RNA polymerase II promoter skeletal muscle tissue development regulation of cell fate commitment regulation of gene expression skeletal muscle satellite cell commitment spinal cord association neuron differentiation dorsal/ventral neural tube patterning positive regulation of histone methylation regulation of protein binding skeletal muscle tissue regeneration neuron fate commitment embryonic skeletal system development cartilage development muscle tissue morphogenesis positive regulation of myoblast proliferation transcription, DNA-templated anatomical structure morphogenesis negative regulation of apoptotic process negative regulation of transcription from RNA polymerase II promoter circadian rhythm cell differentiation response to drug regulation of cell differentiation positive regulation of cell differentiation response to cAMP retina development in camera-type eye pattern specification process urogenital system development metanephros development ureteric bud development branching involved in ureteric bud morphogenesis cell fate determination kidney development mesonephros development neural tube closure optic cup morphogenesis involved in camera-type eye development mesenchymal to epithelial transition involved in metanephros morphogenesis retinal pigment epithelium development mesodermal cell fate specification aging positive regulation of cell proliferation glial cell differentiation optic nerve development optic nerve morphogenesis optic nerve structural organization vestibulocochlear nerve formation pancreas development response to nutrient levels regulation of metanephros size ureter maturation pronephric field specification inner ear morphogenesis regulation of apoptotic process camera-type eye development regulation of programmed cell death negative regulation of programmed cell death negative regulation of cysteine-type endopeptidase activity involved in apoptotic process protein kinase B signaling negative regulation of cytolysis animal organ development pronephros development brain morphogenesis stem cell differentiation positive regulation of epithelial cell proliferation oxidation-reduction process mesenchymal to epithelial transition paramesonephric duct development optic chiasma development cellular response to hydrogen peroxide cellular response to mechanical stimulus cellular response to retinoic acid cellular response to glucose stimulus cellular response to epidermal growth factor stimulus renal system development metanephric mesenchyme development positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis metanephric mesenchymal cell differentiation mesonephric tubule development mesonephric tubule formation mesonephric duct development nephric duct formation ureter development ureter morphogenesis metanephric collecting duct development metanephric epithelium development metanephric distal convoluted tubule development metanephric nephron tubule formation positive regulation of metanephric glomerulus development negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis regulation of metanephric nephron tubule epithelial cell differentiation reactive oxygen species metabolic process cochlea development cochlea morphogenesis positive regulation of branching involved in ureteric bud morphogenesis negative regulation of mesenchymal cell apoptotic process involved in metanephros development negative regulation of apoptotic process involved in metanephric collecting duct development negative regulation of apoptotic process involved in metanephric nephron tubule development negative regulation of reactive oxygen species metabolic process positive regulation of metanephric DCT cell differentiation positive regulation of optic nerve formation humoral immune response multicellular organism development spermatogenesis lateral ventricle development cerebral cortex development adult behavior skeletal muscle cell differentiation embryonic cranial skeleton morphogenesis negative regulation of histone H3-K9 methylation regulation of transcription, DNA-templated thyroid gland development cellular response to gonadotropin stimulus positive regulation of thyroid hormone generation regulation of thyroid-stimulating hormone secretion establishment of mitotic spindle orientation blood vessel development neural crest cell migration neuron migration negative regulation of protein phosphorylation positive regulation of neuroblast proliferation epithelial cell development lens development in camera-type eye type B pancreatic cell differentiation pancreatic A cell differentiation pancreatic A cell development smoothened signaling pathway axonogenesis axon guidance brain development salivary gland morphogenesis negative regulation of cell proliferation regulation of asymmetric cell division dorsal/ventral axis specification anterior/posterior pattern specification dorsal/ventral pattern formation positive regulation of gene expression regulation of neuron projection development pallium development rhombomere morphogenesis olfactory bulb development oligodendrocyte cell fate specification cerebral cortex regionalization forebrain anterior/posterior pattern specification forebrain dorsal/ventral pattern formation commitment of neuronal cell to specific neuron type in forebrain forebrain-midbrain boundary formation regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment telencephalon regionalization pituitary gland development interkinetic nuclear migration signal transduction involved in regulation of gene expression keratinocyte differentiation regulation of cell migration positive regulation of epithelial cell differentiation forebrain development hindbrain development lacrimal gland development protein localization to organelle eye photoreceptor cell development glucose homeostasis positive regulation of cell fate specification cell fate commitment regulation of neuron differentiation negative regulation of neuron differentiation regulation of timing of cell differentiation embryonic camera-type eye morphogenesis astrocyte differentiation negative regulation of epithelial cell proliferation regulation of neurogenesis iris morphogenesis cornea development in camera-type eye neural precursor cell proliferation positive regulation of glucagon secretion insulin metabolic process negative regulation of neural precursor cell proliferation positive regulation of neuron migration central nervous system development response to wounding protein ubiquitination spinal cord development cerebellum development cellular response to insulin stimulus cellular response to drug cellular response to fibroblast growth factor stimulus response to ethanol negative regulation of neurogenesis cellular response to prostaglandin E stimulus endocrine pancreas development visual perception biological_process eye development sulfur compound metabolic process otic vesicle development metanephric comma-shaped body morphogenesis metanephric S-shaped body morphogenesis heart development regulation of somitogenesis cell migration neural tube development gliogenesis developmental pigmentation skeletal muscle organ development mammary gland specification cardiac muscle cell differentiation thyroid-stimulating hormone signaling pathway
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