Osenses

Pan RAB Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

OSR00342W-100UL

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-

Immunohistochemistry (IHC)

1:1,000
-

Miscellaneous PubMed (MISC)

-
View 1 publication 1 publication
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / Ig

Class

Polyclonal

Type

Antibody

Immunogen

A synthetic peptide from internal region of mouse RAB3A conjugated to blue carrier protein has been used as the antigen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

Conc. Not Determined

Storage buffer

whole serum

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

The antigen is homologous or shares a significant identity with many RAB molecules including RAB1, RAB2, RAB4, RAB9, RAB10, RAB11, RAB14, RAB26, RAB30, RAB35, RAB39, RAB43.

Specificity of this antibody: RAB.

Target Information

Rab GTPases regulate many steps of membrane trafficking, including vesicle formation, vesicle movement along actin and tubulin networks, and membrane fusion by recruiting specific effector proteins to restricted membranes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: 24KG; bA165P4.3 (member RAS oncogene family); F protein-binding protein 1; GTP binding protein Rab1a; GTP-binding protein; GTP-binding protein RAB10; GTP-binding protein RAB2B; GTP-binding protein RAY; GTP-binding protein YPT3; GTPase Rab14; HTLV-1 related endogenous sequence; RAB 11A, member oncogene family; Rab GTPase YPT1 homolog; Rab-11; Rab-39; Rab-9-like protein; rab-9A; Rab-9L; rab-related GTP-binding protein; RAB1, member RAS oncogene family; RAB11B, member of RAS oncogene family; RAB1B-like, member RAS oncogene family; RAB2, member RAS oncogene family; RAB39, member RAS oncogene family; RAB9, member RAS oncogene family; RAS family, member RAB2B; RAS oncogene family protein; RAS-associated protein RAB3A; ras-related GTP-binding protein; ras-related GTP-binding protein 4b; Ras-related oncogene protein; Ras-related protein Rab-10; Ras-related protein Rab-11A; Ras-related protein Rab-11B; Ras-related protein Rab-14; Ras-related protein Rab-1A; Ras-related protein Rab-1B; Ras-related protein Rab-1C; ras-related protein rab-1c (GTP-binding protein ray); Ras-related protein Rab-26; Ras-related protein Rab-2A; Ras-related protein Rab-2B; Ras-related protein Rab-30; Ras-related protein Rab-35; Ras-related protein Rab-39A; Ras-related protein Rab-39B; Ras-related protein Rab-3A; Ras-related protein Rab-41; Ras-related protein Rab-43; Ras-related protein Rab-4A; Ras-related protein Rab-4B; Ras-related protein Rab-9A; Ras-related protein Rab-9B; ras-related protein rab10; Ras-related protein RAB43; Ras-related small GTP binding protein 3A; Ras-related small GTP binding protein 4; ras-related YPT1 protein; SID 99; small GTP binding protein RAB14; small GTP binding protein RAB2A; small GTP binding protein RAB4B; small GTP-binding protein; YL8; YPT1-related protein

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Gene Aliases: 0610030G24Rik; 1110011F09Rik; 1500012D09Rik; 1500031G17Rik; 1810048P08Rik; 2410064E05Rik; 2500004H21Rik; 2810475J17Rik; 4930528G15Rik; 5033421K01Rik; 6330580M05Rik; 9330148M11Rik; 9330195C02Rik; 9530019H02Rik; A230002G14; A730055L17Rik; A830020M03Rik; A830021G03Rik; Ac1075; Ac2-048; AI195561; AI314285; AI323892; AI649155; AI848268; AU040256; AW107754; AW490415; C230094F14Rik; C80220; D030017L14Rik; D530043M21Rik; FBP; Gtbp; H-ray; H-YPT3; HRES-1; HRES-1/RAB4; HRES1; LHX; mKIAA3012; MRX72; PP1596; Rab-1; RAB-14; Rab-9L; RAB1; RAB10; RAB11; RAB11A; RAB11B; RAB14; RAB1A; RAB1B; Rab1bl; RAB1C; Rab1r; RAB2; RAB26; RAB2A; RAB2B; RAB3; RAB30; RAB35; RAB39; RAB39A; RAB39B; RAB3A; RAB4; RAB41; RAB43; RAB4A; RAB4B; RAB9; RAB9A; RAB9B; RAB9L; RAY; RGD1562951; Rsb30; Sid6061p; Sid99; V46133; WSMN; YL8; YPT1; YPT3

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UniProt ID: (Human) P61026, (Human) P62491, (Human) Q15907, (Human) P61106, (Human) P62820, (Human) Q9H0U4, (Human) Q9ULW5, (Human) P61019, (Human) Q8WUD1, (Human) Q15771, (Human) Q15286, (Human) Q14964, (Human) Q96DA2, (Human) P20336, (Human) Q86YS6, (Human) P20338, (Human) P61018, (Human) P51151, (Human) Q9NP90, (Mouse) P62821, (Mouse) P61027, (Rat) P62494, (Mouse) P62492, (Rat) O35509, (Mouse) P46638, (Mouse) Q91V41, (Rat) P61107, (Rat) Q6NYB7, (Mouse) Q9D1G1, (Mouse) Q504M8, (Rat) P51156, (Mouse) P53994, (Rat) P05712, (Mouse) P59279, (Mouse) Q923S9, (Mouse) Q6PHN9, (Rat) Q5U316, (Mouse) Q8BHD0, (Mouse) Q8BHC1, (Rat) P63012, (Mouse) P63011, (Mouse) Q8CG50, (Rat) Q53B90, (Rat) P05714, (Mouse) P56371, (Rat) P51146, (Mouse) Q91ZR1, (Mouse) Q9R0M6, (Rat) Q99P75, (Mouse) Q8BHH2

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Entrez Gene ID: (Human) 10890, (Human) 8766, (Human) 9230, (Human) 51552, (Human) 5861, (Human) 81876, (Human) 25837, (Human) 5862, (Human) 84932, (Human) 27314, (Human) 11021, (Human) 54734, (Human) 116442, (Human) 5864, (Human) 339122, (Human) 5867, (Human) 53916, (Human) 9367, (Human) 51209, (Mouse) 19324, (Mouse) 19325, (Rat) 50993, (Rat) 81830, (Mouse) 53869, (Rat) 79434, (Mouse) 19326, (Mouse) 68365, (Rat) 94197, (Rat) 81754, (Rat) 100126191, (Mouse) 76308, (Mouse) 328778, (Rat) 171111, (Mouse) 59021, (Rat) 65158, (Rat) 305853, (Mouse) 76338, (Rat) 308821, (Mouse) 75985, (Mouse) 77407, (Rat) 288700, (Mouse) 270160, (Rat) 315668, (Mouse) 67790, (Rat) 25531, (Mouse) 19339, (Mouse) 69834, (Rat) 500249, (Rat) 25532, (Mouse) 19341, (Rat) 50866, (Mouse) 19342, (Mouse) 56382, (Rat) 84589, (Rat) 367915, (Mouse) 319642

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Function(s)
GTPase activity protein binding GTP binding GDP binding myosin V binding cadherin binding involved in cell-cell adhesion microtubule binding syntaxin binding glycoprotein binding GMP binding phosphatidylinositol-4,5-bisphosphate binding ATPase activator activity protein C-terminus binding GTPase binding ATPase binding protein transporter activity ionotropic glutamate receptor binding molecular_function nucleotide binding
Process(es)
intracellular protein transport exocytosis mitotic metaphase plate congression metabolic process positive regulation of epithelial cell migration regulation of multivesicular body size positive regulation of G2/M transition of mitotic cell cycle vesicle-mediated transport astral microtubule organization neuron projection development melanosome transport Rab protein signal transduction multivesicular body assembly positive regulation of axon extension regulation of long-term neuronal synaptic plasticity regulation of protein transport establishment of vesicle localization regulation of vesicle-mediated transport establishment of protein localization to organelle protein localization to plasma membrane establishment of protein localization to membrane mitotic spindle assembly exosomal secretion autophagosome assembly ER to Golgi vesicle-mediated transport endocytosis autophagy cell migration virion assembly growth hormone secretion defense response to bacterium vesicle transport along microtubule interleukin-8 secretion establishment of endothelial intestinal barrier positive regulation of glycoprotein metabolic process regulation of autophagosome assembly transport small GTPase mediated signal transduction protein transport phagosome acidification phagosome-lysosome fusion cytokinesis renal water homeostasis plasma membrane to endosome transport positive regulation of exocytosis Golgi organization substrate adhesion-dependent cell spreading cargo loading into COPII-coated vesicle retrograde vesicle-mediated transport, Golgi to ER COPII vesicle coating vesicle docking involved in exocytosis protein secretion regulation of exocytosis exocrine system development Golgi to plasma membrane protein transport regulated exocytosis lipid particle organization retrograde transport, endosome to Golgi retrograde transport, plasma membrane to Golgi phagosome maturation toxin transport respiratory system process mitochondrion organization neurotransmitter secretion neuromuscular synaptic transmission axonogenesis post-embryonic development glutamate secretion synaptic vesicle exocytosis synaptic vesicle maturation lung development regulation of synaptic vesicle fusion to presynaptic membrane positive regulation of ATPase activity synaptic vesicle recycling constitutive secretory pathway regulation of short-term neuronal synaptic plasticity maintenance of presynaptic active zone structure sensory perception of touch response to electrical stimulus evoked neurotransmitter secretion positive regulation of regulated secretory pathway Golgi to plasma membrane transport endosomal transport antigen processing and presentation cellular response to insulin stimulus establishment of neuroblast polarity endoplasmic reticulum tubular network organization establishment of protein localization to endoplasmic reticulum membrane synapse organization protein localization endocytic recycling protein localization to endosome cellular response to nerve growth factor stimulus receptor recycling transferrin transport insulin secretion involved in cellular response to glucose stimulus regulation of anion transport cellular response to acidic pH retrograde transport, endosome to plasma membrane regulation of protein localization to cell surface regulation of endocytic recycling cilium assembly cell-cell adhesion regulation of endocytosis glucose import polarized epithelial cell differentiation basolateral protein localization cellular response to antibiotic regulation of protein localization negative regulation by host of symbiont molecular function Golgi to endosome transport body fluid secretion fibroblast growth factor receptor signaling pathway embryo development apical protein localization phagolysosome assembly involved in apoptotic cell clearance intracellular transport membrane organization cell cycle synaptic vesicle transport regulation of long-term synaptic potentiation
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