Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search Thermo Fisher Scientific

Search All
Search button Close
          • Order Status
          • Quick Order
          • Sign in
            Sign in
            Don't have an account ? Create Account
            • Account
            • Check Order Status
            • Aspire Member Program
            • Connect: Lab, Data, Apps
            • Custom Products & Projects
            • Services Central

          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Rho Pan Antibodies

          Osenses

          Pan RhO Polyclonal Antibody

          3 References
          View all (7) Rho Pan antibodies

          Promotion

          View available promotion(s)

          Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite Pan RhO Polyclonal Antibody

          Product Details

          OSR00297G-500UG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          10-50 µg/mL
          -

          Immunohistochemistry (IHC)

          10-50 µg/mL
          -

          Miscellaneous PubMed (MISC)

          -
          View 3 publications 3 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from aa region 50-100 of human Rho-related GTP-binding proteins (RhOA, RhOB, RhOC, RhOF, RhOQ) and RAC1, RAC2, RAC3 and CDC42 conjugated to an immunogenic carrier protein was used as the antigen
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Purification

          Ammonium sulfate precipitation

          Storage buffer

          PBS

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.

          The peptide is homologous in many other species.

          Specificity of this antibody: RhO family.

          Target Information

          This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog 9 (RhoC); aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; aplysia ras-related homolog B; epididymis secretory protein Li 42; h12; h6; h9; induced in fatty liver dystrophy 1; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog 9 (RhoC); ras homolog A1; ras homolog A2; ras homolog B; ras homolog family member F (in filopodia); ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member AB; ras homolog gene family, member B; ras homolog gene family, member C; ras homolog gene family, member F (in filopodia); ras homolog gene family, member Q; Ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; ras-related GTP-binding protein TC10; RAS-related homolog 9; Rho cDNA clone 12; Rho cDNA clone 6; Rho cDNA clone 9; rho family; Rho family GTPase; Rho family GTPase Rif; Rho in filopodia; Rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; Rho-related GTP-binding protein RhoF; Rho-related GTP-binding protein RhoQ; rhoB; rhoC GTPase; SIG-61; Silica-induced gene 61 protein; small GTP binding protein RhoA; small GTP binding protein RhoC; small GTPase Tc10; Transforming protein RhoA

          View more View less

          Gene Aliases: AA017882; AI324259; AI845056; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; ARHB; ARHC; ARHF; ARHQ; AV026554; H9; HEL-S-42; Ifld1; MST081; MSTP081; RASL7A; RHO12; RHOA; RHOB; RHOC; RHOF; RHOH12; RHOH6; RHOH9; RHOQ; RIF; TC10; TC10A

          View more View less

          UniProt ID: (Human) P61586, (Human) P62745, (Human) P08134, (Human) Q9HBH0, (Human) P17081, (Mouse) Q9QUI0, (Rat) P61589, (Mouse) P62746, (Rat) P62747, (Mouse) Q62159, (Mouse) Q8BYP3, (Mouse) Q8R527, (Rat) Q9JJL4

          View more View less

          Entrez Gene ID: (Human) 387, (Human) 388, (Human) 389, (Human) 54509, (Human) 23433, (Mouse) 11848, (Rat) 117273, (Mouse) 11852, (Rat) 64373, (Mouse) 11853, (Rat) 295342, (Rat) 690130, (Mouse) 23912, (Mouse) 104215, (Rat) 85428

          View more View less

          Function(s)
          GTPase activity protein binding GTP binding myosin binding GDP binding signal transducer activity profilin binding GBD domain binding nucleotide binding protein domain specific binding Rho GDP-dissociation inhibitor binding
          Process(es)
          cytokinesis small GTPase mediated signal transduction positive regulation of I-kappaB kinase/NF-kappaB signaling apical junction assembly wound healing, spreading of cells regulation of small GTPase mediated signal transduction positive regulation of lipase activity skeletal muscle satellite cell migration signal transduction insulin receptor signaling pathway regulation of cell shape actin cytoskeleton organization cortical actin cytoskeleton organization cellular response to insulin stimulus positive regulation of transcription from RNA polymerase II promoter GTP metabolic process negative regulation of glucose import positive regulation of glucose import positive regulation of filopodium assembly negative regulation of establishment of protein localization to plasma membrane actin filament organization metabolic process cell morphogenesis regulation of transcription from RNA polymerase II promoter cytoskeleton organization cell cycle cell adhesion cell-matrix adhesion integrin-mediated signaling pathway Rho protein signal transduction skeletal muscle tissue development regulation of neuron projection development cerebral cortex cell migration forebrain radial glial cell differentiation cell differentiation positive regulation of cell growth regulation of cell migration androgen receptor signaling pathway positive regulation of actin filament polymerization stress-activated protein kinase signaling cascade positive regulation of cytokinesis negative regulation of intracellular steroid hormone receptor signaling pathway regulation of osteoblast proliferation cleavage furrow formation apolipoprotein A-I-mediated signaling pathway response to drug negative regulation of I-kappaB kinase/NF-kappaB signaling stress fiber assembly positive regulation of cysteine-type endopeptidase activity involved in apoptotic process negative regulation of neuron apoptotic process positive regulation of neuron apoptotic process ossification involved in bone maturation negative regulation of neuron differentiation positive regulation of neuron differentiation positive regulation of smooth muscle contraction regulation of dendrite development negative chemotaxis cell division positive regulation of stress fiber assembly regulation of calcium ion transport negative regulation of cell death trabecula morphogenesis positive regulation of podosome assembly mitotic spindle assembly regulation of neural precursor cell proliferation regulation of actin cytoskeleton organization angiogenesis transport intracellular protein transport apoptotic process obsolete transformed cell apoptotic process multicellular organism development endosome to lysosome transport protein transport positive regulation of apoptotic process positive regulation of angiogenesis negative regulation of cell cycle cellular response to hydrogen peroxide cellular response to ionizing radiation response to hypoxia regulation of actin polymerization or depolymerization response to mechanical stimulus response to glucose substantia nigra development positive regulation of cell migration response to amino acid response to ethanol positive regulation of translation positive regulation of cell adhesion positive regulation of vasoconstriction neuron projection morphogenesis response to glucocorticoid cellular response to progesterone stimulus transforming growth factor beta receptor signaling pathway viral process cell migration platelet activation actin cytoskeleton reorganization Roundabout signaling pathway positive regulation of NF-kappaB import into nucleus endothelial cell migration vascular endothelial growth factor receptor signaling pathway ephrin receptor signaling pathway phosphatidylinositol-mediated signaling negative regulation of axonogenesis positive regulation of axonogenesis Wnt signaling pathway, planar cell polarity pathway positive regulation of protein serine/threonine kinase activity negative regulation of cell migration involved in sprouting angiogenesis endothelial tube lumen extension mitotic cleavage furrow formation regulation of cell motility positive regulation of endothelial cell migration negative regulation of cell migration endothelial tube morphogenesis
          It has to be done as per old AB suggested Products section.
          guarantee_icon

          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
          help_icon

          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

          Contact tech support
          Ordering Plus Icon Minus Icon
          • Order Status
          • Order Help
          • Quick Order
          • Supply Center
          • eProcurement
          Support Plus Icon Minus Icon
          • Help and Support
          • Contact Us
          • Technical Support Centers
          • Documents and Certificates
          • Report a Site Issue
          Resources Plus Icon Minus Icon
          • Learning Centers
          • Promotions
          • Events and Webinars
          • Social Media
          About Thermo Fisher Plus Icon Minus Icon
          • About Us
          • Careers
          • Investors
          • News
          • Social Responsibility
          • Trademarks
          • Consumer Health Data Privacy Policy
          Our Portfolio Plus Icon Minus Icon
          • Thermo Scientific
          • Applied Biosystems
          • Invitrogen
          • Gibco
          • Ion Torrent
          • Fisher Scientific
          • Unity Lab Services
          • Patheon
          • PPD
          • Terms & Conditions
          • Privacy Information Center
          • Price & Freight Policy
          © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
          United States flag icon
          United States

          Your items have has been added!


          Host server : magellan-search-67c77f6dc7-n6nf2:80/100.66.135.186:80.
          git-commit: 545e792480003146e539d624bd2a21b51d198228
          git-url: https://github.com/thermofisher/magellan-search
          git-branch: release/2.31.0-2025.06.23-1.0