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Invitrogen
Peptidylarginine Deiminase Polyclonal Antibody
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Peptidylarginine Deiminase Antibody (PA5-119333) in IHC (P)
Immunohistochemistry analysis of Peptidylarginine Deiminase in paraffin-embedded Human Spleen tissue. Samples were incubated with polyclonal antibody (Product # PA5-119333) at a dilution of 20 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
Product Details
PA5-119333
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein Peptidyl Arginine Deiminase Type I. The antigen corresponds to amino acid range 298-556 of the target protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2903831
Target Information
This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hPAD-colony 10; Pad type 1; PAD type I; PADI5; PDI2; PDI3; PDI4; peptidyl arginine deiminase, type I; Peptidylarginine deiminase I; Protein-arginine deiminase type I; PROTEIN-ARGININE DEIMINASE TYPE I (PEPTIDYLARGININE DEIMINASE I); Protein-arginine deiminase type-1
Gene Aliases: AV236283; HPAD10; PAD1; PADI1; PDI; PDI1
UniProt ID: (Human) Q9ULC6, (Mouse) Q9Z185
Entrez Gene ID: (Human) 29943, (Mouse) 18599
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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