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Antibody detects endogenous levels of CdGAP only when phosphorylated at Thr789.
This gene encodes a GTPase-activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC42 GTPase-activating protein; Rho GTPase-activating protein 31
Gene Aliases: 5830477L08Rik; AOS1; ARHGAP31; AU041750; CDGAP; D330026I07Rik; KIAA1204
UniProt ID: (Human) Q2M1Z3, (Mouse) A6X8Z5
Entrez Gene ID: (Human) 57514, (Rat) 288093, (Mouse) 12549
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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