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Phospho-ARHGAP42 (Tyr792) Antibody (PA5-105370) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded Phospho-ARHGAP42 (Tyr792) in human gastric tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with Phospho-ARHGAP42 (Tyr792) polyclonal antibody (Product # PA5-105370) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
Product Details
PA5-105370
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ARHGAP42(Accession A6NI28), corresponding to amino acid residues around phosphorylated Tyr792.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2816798
Product Specific Information
Antibody detects endogenous levels of ARHGAP42 only when phosphorylated at Tyr792.
Target Information
This gene encodes a Rho GTPase-activating protein (RhoGAP), and member of the GRAF or BAR-PH family of proteins. Expression of this gene is enriched in vascular smooth muscle cells and the encoded protein inhibits RhoA activity to regulate vascular tone and control blood pressure. A mutation in the first intron of this gene modulates its expression and is associated with reduced blood pressure in human patients with borderline hypertension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: arhgap42; Rho GTPase activating protein 42; Rho GTPase-activating protein 10-like; Rho GTPase-activating protein 42; Rho-type GTPase-activating protein 42; VRho GTPase activating protein 42
Gene Aliases: 9030420J04Rik; ARHGAP42; BE136619; GRAF3; RGD1564081; TMEM133
UniProt ID: (Human) A6NI28, (Mouse) B2RQE8
Entrez Gene ID: (Human) 143872, (Mouse) 71544, (Rat) 500943
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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