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Phospho-BRIP1 (Thr1133) Antibody (PA5-105227) in WB
Western blot analysis of Phospho-BRIP1 (Thr1133) in Jurkat cell lysate (Lane 1: treated with phospho-blocking peptide; Lane 2: treated with non-phospho-blocking peptide). Samples were incubated with Phospho-BRIP1 (Thr1133) polyclonal antibody (Product # PA5-105227).
Product Details
PA5-105227
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BRIP1(Accession Q9BX63), corresponding to amino acid residues around phosphorylated Thr1133.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2816700
Product Specific Information
Antibody detects endogenous levels of BACH1/BRIP1 only when phosphorylated at Thr1133.
Target Information
LIN54 is a component of the LIN, or DREAM, complex, an essential regulator of cell cycle genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent RNA helicase BRIP1; BACH 1; BACH1 BRIP1; BRCA1-associated C-terminal helicase 1; BRCA1-binding helicase-like protein BACH1; BRCA1-interacting protein 1; BRCA1-interacting protein C-terminal helicase 1; BRCA1/BRCA2-associated helicase 1; BRIP 1; DNA 5'-3' helicase FANCJ; FANCJ protein; Fanconi anemia group J protein; FLJ90232; MGC126521; MGC126523
Gene Aliases: BACH1; BRIP1; FANCJ; OF
UniProt ID: (Human) Q9BX63
Entrez Gene ID: (Human) 83990
DNA damage checkpoint
DNA synthesis involved in DNA repair
strand displacement
DNA replication
double-strand break repair
regulation of transcription from RNA polymerase II promoter
negative regulation of cell proliferation
DNA duplex unwinding
cellular response to vitamin
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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