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Invitrogen
Phospho-C2orf33 (Ser172, Ser146) Polyclonal Antibody
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Phospho-C2orf33 (Ser172, Ser146) Antibody (PA5-104614) in IHC (P)
Immunohistochemistry analysis of Phospho-C2orf33 (Ser172, Ser146) in human esophageal cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-C2orf33 (Ser172, Ser146) polyclonal antibody (Product # PA5-104614) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-104614
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MFF(Accession Q9GZY8), corresponding to amino acid residues around phosphorylated Ser172.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2816089
Product Specific Information
Antibody detects endogenous levels of MFF only when phosphorylated at Ser172/146.
Target Information
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. [Uniprot]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Mitochondrial fission factor
Gene Aliases: AD030; AD033; C2orf33; GL004; MFF
UniProt ID: (Human) Q9GZY8
Entrez Gene ID: (Human) 56947
mitochondrial fission
release of cytochrome c from mitochondria
protein targeting to mitochondrion
mitochondrial fusion
regulation of mitochondrion organization
peroxisome fission
mitochondrial fragmentation involved in apoptotic process
protein homooligomerization
mitochondrion morphogenesis
positive regulation of mitochondrial fission
positive regulation of release of cytochrome c from mitochondria
positive regulation of protein targeting to membrane
regulation of peroxisome organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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