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Invitrogen
Phospho-CAMKK alpha/beta (Ser458, Ser495) Polyclonal Antibody
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FIGURE: 1 / 10
Phospho-CAMKK alpha/beta (Ser458, Ser495) Antibody (PA5-105869) in IHC (P)
Immunohistochemistry analysis of Phospho-CAMKK alpha/beta (Ser458, Ser495) in human gastric cancer and adjacent normal tissues. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with Phospho-CAMKK alpha/beta (Ser458, Ser495) polyclonal antibody (Product # PA5-105869) using a dilution of 1:100 (4°C overnight) followed by HRP c... View More
Product Details
PA5-105869
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CAMKK1(Accession Q8N5S9), corresponding to amino acid residues around phosphorylated Ser458.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2817268
Product Specific Information
Antibody detects endogenous levels of CAMKK1/2 only when phosphorylated at Ser458/495.
Target Information
The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade. Three transcript variants encoding two distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: alpha CaMKK; Ca+/Calmodulin-dependent protein kinase kinase beta (CaM-kinase kinase beta); calcium calmodulin dependent protein kinase kinase alpha; calcium/calmodulin-dependent protein kinase 2 beta; calcium/calmodulin-dependent protein kinase beta; Calcium/calmodulin-dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; Calcium/calmodulin-dependent protein kinase kinase 2; calcium/calmodulin-dependent protein kinase kinase 2, beta; Calcium/calmodulin-dependent protein kinase kinase alpha; Calcium/calmodulin-dependent protein kinase kinase beta; CaM-kinase IV kinase; caM-kinase kinase 1; caM-kinase kinase 2; caM-kinase kinase alpha; CaM-kinase kinase beta; CaM-KK 1; CaM-KK 2; CaM-KK alpha; CaM-KK beta; caMKK 1; caMKK 2; caMKK alpha; CAMKK alpha protein; caMKK beta; CAMKK beta protein
Gene Aliases: 6330570N16Rik; AI846603; AW061083; CAMKK; CAMKK1; CAMKK2; CAMKKA; CaMKKalpha; CAMKKB; KIAA0787; mKIAA0787
UniProt ID: (Human) Q8N5S9, (Human) Q96RR4, (Mouse) Q8VBY2, (Rat) P97756, (Rat) O88831, (Mouse) Q8C078
Entrez Gene ID: (Human) 84254, (Human) 10645, (Mouse) 55984, (Rat) 60341, (Rat) 83506, (Mouse) 207565
calmodulin-dependent protein kinase activity
protein binding
calmodulin binding
ATP binding
protein tyrosine kinase activity
calcium ion binding
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein kinase activator activity
MAPK cascade
protein phosphorylation
peptidyl-tyrosine phosphorylation
calcium-mediated signaling
regulation of protein kinase activity
positive regulation of transcription, DNA-templated
protein autophosphorylation
activation of protein kinase activity
phosphorylation
positive regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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