Invitrogen

Phospho-CDK1/CDK2 (Thr14) Polyclonal Antibody

View all (3) CDK1/CDK2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-67509

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:3,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthesized peptide derived from human CDK1/CDK2 around the phosphorylation site of Thr14.
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2691675

Product Specific Information

Predicted to react with Mouse and Rat samples.

Target Information

Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: cdc2-related protein kinase; CDK1; cell cycle controller CDC2; cell cycle p34 CDC2 kinase protein; Cell division control protein 2 homolog; cell division cycle 2 homolog A; cell division cycle 2, G1 to S and G2 to M; Cell division cycle control protein 2; cell division cycle control protein 2a; Cell division protein kinase 1; Cell division protein kinase 2; cyclin dependent kinase 2-alpha; Cyclin-dependent kinase 1; Cyclin-dependent kinase 2; p33 protein kinase; p34 protein kinase

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Gene Aliases: A630093N05Rik; CDC2; CDC28A; Cdc2a; CDK1; CDK2; CDKN1; CDKN2; p33(CDK2); p34; P34CDC2

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UniProt ID: (Human) P06493, (Human) P24941, (Rat) P39951, (Mouse) P11440, (Mouse) P97377

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Entrez Gene ID: (Human) 983, (Human) 1017, (Rat) 54237, (Mouse) 12534, (Rat) 362817, (Mouse) 12566

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Function(s)
protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity cyclin binding Hsp70 protein binding histone kinase activity kinase activity protein complex binding metal ion binding nucleotide binding transferase activity transferase activity, transferring phosphorus-containing groups
Process(es)
mitotic cell cycle protein complex assembly protein phosphorylation apoptotic process mitotic nuclear division mitotic G2 DNA damage checkpoint cell aging response to toxic substance response to organonitrogen compound positive regulation of gene expression response to organic cyclic compound response to amine response to activity histone phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation chromosome condensation epithelial cell differentiation organ regeneration positive regulation of protein import into nucleus, translocation protein localization to kinetochore response to drug response to hydrogen peroxide negative regulation of apoptotic process response to ethanol positive regulation of DNA replication positive regulation of mitotic cell cycle response to cadmium ion response to copper ion response to axon injury cell division ventricular cardiac muscle cell development positive regulation of cardiac muscle cell proliferation cellular response to hydrogen peroxide G1/S transition of mitotic cell cycle lens development in camera-type eye DNA repair potassium ion transport Ras protein signal transduction positive regulation of cell proliferation positive regulation of DNA-dependent DNA replication initiation response to estradiol cellular response to insulin stimulus positive regulation of transcription, DNA-templated meiotic cell cycle response to cAMP response to electrical stimulus regulation of cell cycle regulation of gene silencing cell cycle phosphorylation cellular response to DNA damage stimulus G2/M transition of mitotic cell cycle DNA replication DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest centriole replication meiotic nuclear division mitotic G1 DNA damage checkpoint centrosome duplication negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle cellular response to nitric oxide regulation of signal transduction by p53 class mediator regulation of transcription involved in G1/S transition of mitotic cell cycle activation of MAPK activity microtubule cytoskeleton organization mitotic nuclear envelope disassembly centrosome cycle pronuclear fusion regulation of Schwann cell differentiation cell migration anaphase-promoting complex-dependent catabolic process protein ubiquitination involved in ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process regulation of embryonic development positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition Golgi disassembly positive regulation of protein localization to nucleus
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