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Invitrogen
Phospho-CRMP2 (Thr514) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-CRMP2 (Thr514) Antibody (PA5-110113) in WB
Western blot analysis of Phospho-CRMP2 (Thr514) in extracts of various cell lines. Samples were incubated with Phospho-CRMP2 (Thr514) Polyclonal antibody (Product # PA5-110113) using a dilution of 1:1,000 or CRMP2/DPYSL2 antibody. Followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. SH-SY5Y cells were treated by CIP (20 µL/400 µL) at 37°C for 1 hour. PC-12 cells were trea... View More
Product Details
PA5-110113
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic phosphorylated peptide around T514 of human CRMP2/DPYSL2 (NP_0013771)
Conjugate
Form
Liquid
Concentration
1.27 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855524
Product Specific Information
Immunogen sequence: TVTPA
Target Information
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collapsin response mediator protein 2; collapsin response mediator protein hCRMP-2; CRMP-2; dihydropyrimidinase-like 2; Dihydropyrimidinase-related protein 2; DPYL2; DRP-2; N2A3; TOAD-64; Turned on after division 64 kDa protein; turned on after division, 64 kDa protein; ULIP-2; Unc-33-like phosphoprotein 2
Gene Aliases: AI851130; CRMP-2; CRMP2; DHPRP2; DPYSL2; DRP-2; DRP2; Musunc33; N2A3; TOAD-64; ULIP-2; ULIP2
UniProt ID: (Human) Q16555, (Rat) P47942, (Mouse) O08553
Entrez Gene ID: (Human) 1808, (Rat) 25416, (Mouse) 12934
response to amphetamine
pyrimidine nucleobase catabolic process
endocytosis
cytoskeleton organization
brain development
regulation of neuron projection development
positive regulation of glutamate secretion
spinal cord development
olfactory bulb development
regulation of axon extension
response to cocaine
response to drug
regulation of neuron differentiation
synaptic vesicle transport
nucleobase-containing compound metabolic process
signal transduction
nervous system development
axon guidance
multicellular organism development
cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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