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Phospho-Cdc25B (Ser187) Antibody (PA5-85380) in WB
Western Blot using Phospho-Cdc25B (Ser187) Polyclonal Antibody (Product # PA5-85380). Sample (30 µg of whole cell lysate). Lane A: U87-MG . 7.5% SDS PAGE. Phospho-Cdc25B (Ser187) Polyclonal Antibody (Product # PA5-85380) diluted at 1:1,000.
Product Details
PA5-85380
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human CDC25B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792522
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (93%), Rat (92%), Pig (93%), Bovine (93%).
Positive Control: NT2D1, U87-MG.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
Gene Aliases: CDC25B; CDC25HU2
UniProt ID: (Human) P30305
Entrez Gene ID: (Human) 994
G2/M transition of mitotic cell cycle
mitotic cell cycle
oocyte maturation
protein phosphorylation
mitotic nuclear division
female meiosis I
positive regulation of cell proliferation
positive regulation of cytokinesis
peptidyl-tyrosine dephosphorylation
positive regulation of protein kinase activity
positive regulation of mitotic cell cycle
cell division
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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