Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Phospho-Claspin (Ser30) Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
FIGURE: 1 / 5
Phospho-Claspin (Ser30) Antibody (PA5-105980) in ICC/IF
Immunocytochemistry analysis of Phospho-Claspin (Ser30) in Hela cells (4h of LPS treatment). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Phospho-Claspin (Ser30) polyclonal antibody (Product # PA5-105980) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbi... View More
Product Details
PA5-105980
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CLSPN(Accession Q9HAW4), corresponding to amino acid residues around phosphorylated Ser30.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2817379
Product Specific Information
Antibody detects endogenous levels of Claspin only when phosphorylated at Ser30.
Target Information
Xenopus claspin is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in the presence of DNA templates in Xenopus egg extracts. The human gene appears to be the homolog Xenopus claspin and its function has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Claspin; claspin homolog; hClaspin; MGC131612; MGC131613; MGC131615
Gene Aliases: B130025E01; C85083; CLSPN; E130314M08Rik
UniProt ID: (Human) Q9HAW4, (Mouse) Q80YR7
Entrez Gene ID: (Human) 63967, (Rat) 298534, (Mouse) 269582
DNA damage checkpoint
peptidyl-serine phosphorylation
activation of protein kinase activity
mitotic DNA replication checkpoint
DNA replication checkpoint
DNA repair
cellular response to DNA damage stimulus
cell cycle
G2 DNA damage checkpoint
DNA replication
cellular component disassembly involved in execution phase of apoptosis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support