Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Phospho-CtBP1/CtBP2 (Ser158, Ser164) Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-64665
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CtBP1/2 (Phospho-Ser158/164)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2663240
Product Specific Information
Phospho-CtBP1/CtBP2 (Ser158, 164) Polyclonal Antibody detects endogenous levels of CtBP1/CtBP2 only when phosphorylated at Ser158, 164.
Target Information
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: brefeldin A-ribosylated substrate; C-terminal-binding protein 1; C-terminal-binding protein 2; CtBP1; CtBP2; ribeye
Gene Aliases: BARS; CTBP; CTBP1; CTBP2
UniProt ID: (Human) Q13363, (Human) P56545
Entrez Gene ID: (Human) 1487, (Human) 1488
RNA polymerase II transcription corepressor activity
transcription factor activity, sequence-specific DNA binding
protein binding
protein C-terminus binding
transcription factor binding
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
protein domain specific binding
protein homodimerization activity
NAD binding
repressing transcription factor binding
chromatin binding
transcription coactivator activity
transcription corepressor activity
retinoic acid receptor binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
negative regulation of cell proliferation
viral genome replication
positive regulation of chromatin binding
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of retinoic acid receptor signaling pathway
white fat cell differentiation
oxidation-reduction process
protein phosphorylation
positive regulation of histone deacetylation
negative regulation of histone acetylation
regulation of cell cycle
negative regulation of histone H4 acetylation
negative regulation of transcription from RNA polymerase II promoter by histone modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support