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Invitrogen
Phospho-Ephrin B1/B2/B3 (Tyr324/311/318) Polyclonal Antibody
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FIGURE: 1 / 1
Phospho-Ephrin B1/B2/B3 (Tyr324/311/318) Antibody (PA5-37810) in IHC (P)
Immunohistochemical analysis of Phospho-Ephrin B1/B2/B3 (Tyr324) in paraffin-embedded Human brain tissue using Phospho-Ephrin B1/B2/B3 (Tyr324) Polyclonal Antibody (Product # PA5-37810) (left) or the same antibody preincubated with blocking peptide (right).
Product Details
PA5-37810
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence around phosphorylation site of tyrosine 324/311/318 (G-D-Y(p)-G-H) derived from Human Ephrin B1/B2/B3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2554418
Product Specific Information
A suggested positive control for Western blot is K562 cells; suggested positive control for IHC is human brain tissue.
Target Information
Eph receptors and ephrins exhibit complementary expression in many tissues during embryogenesis indicating that bidirectional activation of Eph receptors and ephrin-B proteins may occur at expression domain interfaces. Ephrin-B1 transduces outside-in signals through C-terminal protein interactions that effect integrin-mediated cell attachment and migration. The distribution of ephrin-B1 in the developing retina suggests that it influences retinal axon mapping along the dorsal-ventral axis and may be involved in intratectal development The transmembrane ligand ephrin-B2 and its receptor tyrosine kinase EphB4 are specifically expressed on arterial and venous endothelial cells, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: EFL-3; ELK ligand; ELK-L; EPH-related receptor transmembrane ligand ELK-L3; EPH-related receptor tyrosine kinase ligand 2; EPH-related receptor tyrosine kinase ligand 5; EPH-related receptor tyrosine kinase ligand 8; Ephrin-B1; Ephrin-B2; Ephrin-B3; HTK ligand; HTK-L; LERK-2; LERK-5; LERK-8; ligand of eph-related kinase 5
Gene Aliases: CFND; CFNS; EFB1; EFL3; EFL6; EFNB1; EFNB2; EFNB3; Elk-L; EPLG2; EPLG5; EPLG8; Htk-L; HTKL; LERK2; LERK5; LERK8
UniProt ID: (Human) P98172, (Human) P52799, (Human) Q15768
Entrez Gene ID: (Human) 1947, (Human) 1948, (Human) 1949
cell-cell signaling
nervous system development
axon guidance
adult walking behavior
axon choice point recognition
T cell costimulation
viral entry into host cell
ephrin receptor signaling pathway
lymph vessel development
cell migration involved in sprouting angiogenesis
cell adhesion
anatomical structure morphogenesis
organ morphogenesis
negative regulation of keratinocyte proliferation
regulation of chemotaxis
nephric duct morphogenesis
positive regulation of cardiac muscle cell differentiation
neural crest cell migration
embryonic pattern specification
positive regulation of T cell proliferation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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