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Invitrogen
Phospho-Ephrin B2 (Tyr316) Polyclonal Antibody
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Product Details
PA5-37552
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y(p)-I-V) derived from Human Ephrin-B2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2554161
Product Specific Information
A suggested positive control for Western blot is HT29 cells.
Target Information
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ELF-2; EPH-related receptor tyrosine kinase ligand 5; Ephrin-B2; HTK ligand; HTK-L; LERK-5; ligand of eph-related kinase 5; MGC126226; MGC126227; MGC126228
Gene Aliases: EFNB2; ELF-2; Elf2; Epl5; EPLG5; Htk-L; HTKL; LERK-5; LERK5; NLERK-1
UniProt ID: (Human) P52799, (Mouse) P52800
Entrez Gene ID: (Human) 1948, (Mouse) 13642, (Rat) 306636
angiogenesis
lymph vessel development
cell migration involved in sprouting angiogenesis
cell adhesion
multicellular organism development
nervous system development
axon guidance
organ morphogenesis
negative regulation of keratinocyte proliferation
cell migration
cell differentiation
ephrin receptor signaling pathway
blood vessel morphogenesis
regulation of chemotaxis
nephric duct morphogenesis
positive regulation of cardiac muscle cell differentiation
cell-cell signaling
anatomical structure morphogenesis
T cell costimulation
viral entry into host cell
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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