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Invitrogen
Phospho-JunD (Ser255) Recombinant Rabbit Monoclonal Antibody (JJ08-21)
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FIGURE: 1 / 7
Phospho-JunD (Ser255) Antibody (MA5-32444) in ICC/IF
Immunocytochemical analysis of Phospho-JunD (Ser255) in MCF-7 cells using a Phospho-JunD (Ser255) Monoclonal antibody (Product # MA5-32444) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
MA5-32444
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JJ08-21
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser255 of Human JunD aa 251-270
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2809722
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
JunD is a transcription factor which is coded by JunD gene. JunD transcriptional activity is modulated by phosphorylation in response to cellular stress via the c-Jun N terminal kinase (JNK)/Stress-Activated Protein Kinase (SAPK) family of protein kinase. Jun proteins are capable of forming dimers with Fos, ATF and CREB family transcription factors to form the AP-1 complex that differentially regulates a variety of target genes involved in cellular growth, proliferation, differentiation and apoptosis. Also, JunD plays an important role in metabolism via modulation of IGF-1 signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: activator protein 1; AP1; JUN D; jun D proto-oncogene; Jun proto-oncogene related gene d; Jun proto-oncogene related gene d1; JunD-FL isoform; Oncogene Jun-D; Transcription factor AP-1 subunit JunD; transcription factor jun-D; Transcription factor JunD
Gene Aliases: AP-1; Jun-d; JUND; Jund1
UniProt ID: (Human) P17535, (Rat) P52909, (Mouse) P15066
Entrez Gene ID: (Human) 3727, (Rat) 24518, (Mouse) 16478
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription coactivator activity
protein binding
transcription factor binding
ligand-dependent nuclear receptor binding
enzyme binding
transcription regulatory region DNA binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
protein heterodimerization activity
osteoblast development
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
aging
circadian rhythm
response to light stimulus
response to mechanical stimulus
response to organic cyclic compound
response to lipopolysaccharide
response to peptide hormone
positive regulation of osteoblast differentiation
positive regulation of transcription from RNA polymerase II promoter
cellular response to calcium ion
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
response to radiation
regulation of cell death
cellular response to hormone stimulus
response to cytokine
regulation of cell proliferation
response to drug
positive regulation of cell differentiation
response to cAMP
regulation of cell cycle
transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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