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Invitrogen
Phospho-LEO1 (Ser551) Polyclonal Antibody
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Phospho-LEO1 (Ser551) Antibody (PA5-12993) in DB
Dot blot analysis of Phospho-LEO1 (Ser551). Samples were incubated with Phospho-LEO1 (Ser551) polyclonal antibody (Product # PA5-12993) using a dilution of 0.5 µg/mL. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed on nitrocellulose membrane.
Product Details
PA5-12993
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S551 of human Leo1
Conjugate
Form
Liquid
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2234606
Product Specific Information
This antibody is predicted to react with mouse, rat, Xenopus and zebrafish based on sequence homology.
Target Information
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Leo1 Paf1/RNA polymerase II complex component; Leo1, Paf1/RNA polymerase II complex component, homolog; Replicative senescence down-regulated leo1-like protein; RNA polymerase-associated protein LEO1
Gene Aliases: LEO1; RDL
UniProt ID: (Human) Q8WVC0
Entrez Gene ID: (Human) 123169
endodermal cell fate commitment
transcription elongation from RNA polymerase II promoter
mRNA polyadenylation
histone monoubiquitination
Wnt signaling pathway
stem cell population maintenance
positive regulation of mRNA 3'-end processing
positive regulation of transcription elongation from RNA polymerase II promoter
histone H2B ubiquitination
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
beta-catenin-TCF complex assembly
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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